Aggarwal Geet, Tiwari Aseem K, Arora Dinesh, Dara Ravi C, Acharya Devi P, Bhardwaj Gunjan, Sharma Jyoti
Department of Transfusion Medicine, Medanta - The Medicity, Gurgaon, Haryana, India.
Asian J Transfus Sci. 2018 Jan-Jun;12(1):42-45. doi: 10.4103/ajts.AJTS_31_17.
The authors' center recently changed their pretransfusion testing protocol from "conventional" type and screen (TS) with anti-human globulin (AHG) crossmatch (Policy A) to TS with immediate-spin (IS) crossmatch (Policy B). Red blood cell (RBC) units were issued after compatible IS crossmatch as and when required instead of AHG crossmatch. This study was conducted to compare the effects of change of policy from A to B over 1-year period on crossmatch-to-transfusion (C/T) ratio, RBC issue turnaround time (TAT), outdating of RBC, man-hours consumption, and monetary savings.
This was a comparative, prospective study conducted by the Department of Transfusion Medicine of a tertiary hospital-based blood bank in Northern India. The Policy B was implemented in the department from January 2014. Relevant retrospective data for comparison of the previous 1 year, when Policy A was practiced, were derived from hospital information system.
23909 and 24724 RBC units transfused to patients admitted to the hospital during respective 1-year period of practice for Policy A and B. There was significant reduction in C/T ratio (1.94 vs. 1.01) and RBC issue TAT (79 vs. 65 min) with Policy B. Expiry due to outdating reduced (37 vs. zero) along with man-hours (16% reduction) and monetary (33% reduction) savings.
Use of 'TS with IS crossmatch' policy provides multiple advantages to all the stakeholders; blood banker, clinician, patient, and the hospital management.
作者所在中心最近将输血前检测方案从采用抗人球蛋白(AHG)交叉配血的“传统”血型鉴定和筛查(TS)(政策A)改为采用立即离心(IS)交叉配血的TS(政策B)。红细胞(RBC)单位在需要时经相容的IS交叉配血后发放,而非AHG交叉配血。本研究旨在比较1年期间从政策A改为政策B对交叉配血与输血(C/T)比率、RBC发放周转时间(TAT)、RBC过期情况、人工时消耗和节省费用的影响。
这是一项由印度北部一家三级医院血库输血医学科开展的比较性前瞻性研究。该科室于2014年1月实施政策B。之前实施政策A的1年的相关回顾性数据用于比较,数据来源于医院信息系统。
在政策A和政策B各自实施的1年期间,分别有23909个和24724个RBC单位输注给入院患者。政策B使C/T比率(1.94对1.01)和RBC发放TAT(79分钟对65分钟)显著降低。过期导致的报废减少(37对零),同时节省了人工时(减少16%)和费用(减少33%)。
采用“TS与IS交叉配血”政策为所有利益相关者(血库工作人员、临床医生、患者和医院管理层)带来了多重益处。