在印度环境下，与传统抗球蛋白交叉配血程序相比，血型和筛查方法用于相容性检测的安全性。
Safety of type and screen method compared to conventional antiglobulin crossmatch procedures for compatibility testing in Indian setting.
作者信息
Chaudhary Rajendra, Agarwal Nitin
机构信息
Department of Transfusion Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
出版信息
Asian J Transfus Sci. 2011 Jul;5(2):157-9. doi: 10.4103/0973-6247.83243.
Abstract
BACKGROUND
Over the past 30 years, pretransfusion tests have undergone considerable modification. In 1984, AABB recommended that the full cross match could be replaced by an abbreviated cross match in patients with negative antibody screen. However, before implementation of such a policy, issue regarding safety of T & S needs to be evaluated.
OBJECTIVES
The aim of pretransfusion testing (PTT) is to ensure that enough red blood cells (RBCs) in the selected red cell components will survive when transfused.
RESULTS AND CONCLUSION
We have, therefore in this study; evaluated safety of T & S procedure for PTT in comparison with conventional test tube cross match. The T & S procedure gave a safety of 91.6%. Also, the usefulness of the T & S was shown through the detection of unexpected antibodies in 0.75% (15 out of 2026) of cases.
摘要
背景
在过去30年中，输血前检测经历了相当大的改进。1984年，美国血库协会（AABB）建议，对于抗体筛查呈阴性的患者，完整交叉配血可被简化交叉配血取代。然而，在实施该政策之前，需要评估盐水配血试验（T&S）的安全性问题。
目的
输血前检测（PTT）的目的是确保所选红细胞成分中的足够红细胞在输血后能够存活。
结果与结论
因此，在本研究中，我们评估了盐水配血试验（T&S）用于输血前检测（PTT）相对于传统试管交叉配血的安全性。盐水配血试验（T&S）的安全性为91.6%。此外，通过在0.75%（2026例中的15例）的病例中检测到意外抗体，证明了盐水配血试验（T&S）的有效性。
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