Joshi Amit, Sahu Arvind, Noronha Vanita, Patil Vijay, Prabhash Kumar
Department of Medical Oncology, Tata Memorial Hospital, Mumbai, India.
Indian J Surg Oncol. 2018 Mar;9(1):97-104. doi: 10.1007/s13193-018-0721-2. Epub 2018 Jan 29.
Management of metastatic renal cell carcinoma (mRCC) has evolved considerably in the past 10 years due to better understanding of tumor biology. This development has changed mRCC to a chronic progressive disease with several lines of treatment options. The introduction of several new targeted therapies including immunotherapy has improved median overall survival of approximately 1 year to >2 years in mRCC.
由于对肿瘤生物学有了更深入的了解,转移性肾细胞癌(mRCC)的管理在过去10年中有了显著进展。这一进展已将mRCC转变为一种有多种治疗选择的慢性进展性疾病。包括免疫疗法在内的几种新靶向疗法的引入,已将mRCC的中位总生存期从约1年提高到了2年以上。