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The Future of the RTS,S/AS01 Malaria Vaccine: An Alternative Development Plan.RTS,S/AS01疟疾疫苗的未来:一项替代发展计划。
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A spatial statistical approach to analyze malaria situation at micro level for priority control in Ranchi district, Jharkhand.一种空间统计方法,用于分析恰尔肯德邦兰契地区微观层面的疟疾情况,以便进行重点控制。
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在同一冬季前季节,运用现场流行病学方法对贾坎德邦两个地区疟疾暴发及相关死亡情况进行的流行病学调查比较研究。

A comparative study of epidemiological investigations of malaria outbreaks and related deaths in two districts of Jharkhand during the same prewinter season using shoe-leather epidemiology.

作者信息

Kumar Dewesh, Singh Shashi Bhushan, Kumar Abhishek, Kishore Anupam, Kashyap Vivek

机构信息

Department of PSM, RIMS, Ranchi, Jharkhand, India.

出版信息

J Family Med Prim Care. 2017 Oct-Dec;6(4):744-749. doi: 10.4103/jfmpc.jfmpc_55_17.

DOI:10.4103/jfmpc.jfmpc_55_17
PMID:29564256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5848391/
Abstract

BACKGROUND

Following news of deaths in two districts of Jharkhand (West Singhbum and Garhwa) in November 2016, epidemiological investigations were contemplated to investigate any current outbreak of falciparum malaria and deaths attributed to it.

METHODOLOGY

The epidemiological investigations, verbal autopsy of suspected deaths attributed to malaria and keys interviews were conducted in the 2 and 4 week of November 2016 in Khuntpani and Dhurki block of West Singhbum and Garhwa districts, respectively, following a strict protocol.

RESULTS

The affected villages were Argundi and Korba-Pahariya and their adjacent tolas in Khuntpani and Dhurki block. Undoubtedly, there was the continuous transmission of falciparum malaria in both the regions in October and November 2016. The total cases (according to case definitions) were 1002, of them, 338 and 12 patients were positive for positive (Pf +ve) and positive (Pv +ve), respectively, in the affected areas of Khuntpani block. In Dhurki block, out of the total of 631 patients fulfilling the case definition, 65 patients were PF +ve and 23 Pv +ve. Comparing to the last year, there is remarkably high number of falciparum cases. Verbal autopsy of deceased individuals showed that malaria might be one of the strongly probable diagnoses, but not conclusively.

CONCLUSION

According to epidemiological investigation, verbal autopsy and key interviews conducted, it may be concluded that there is a definite outbreak of falciparum malaria in the area and environment is congenial for malaria and other tropical diseases.

摘要

背景

2016年11月,恰尔肯德邦(西辛格布姆和加瓦尔)两个地区出现死亡消息后,考虑开展流行病学调查,以调查当前是否存在恶性疟暴发及由此导致的死亡情况。

方法

2016年11月的第2周和第4周,分别在西辛格布姆和加瓦尔地区的孔特帕尼和杜尔基街区,按照严格方案开展了流行病学调查、对疑似疟疾死亡病例的死因推断访谈以及关键访谈。

结果

受影响村庄为孔特帕尼和杜尔基街区的阿尔贡迪和科尔巴 - 帕哈里亚及其相邻村落。毫无疑问,2016年10月和11月这两个地区均存在恶性疟的持续传播。(根据病例定义)总病例数为1002例,其中孔特帕尼街区受影响地区分别有338例和12例患者的疟原虫检测呈阳性(Pf阳性)和阳性(Pv阳性)。在杜尔基街区,在符合病例定义的631例患者中,65例为PF阳性,23例为Pv阳性。与去年相比,恶性疟病例数显著增加。对死亡个体的死因推断显示,疟疾可能是极有可能的诊断之一,但不能确定。

结论

根据开展的流行病学调查、死因推断访谈和关键访谈,可以得出结论,该地区确实暴发了恶性疟,且该地区环境适宜疟疾及其他热带疾病的传播。