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首例文昌鱼线粒体假基因的报道(圆口纲:七鳃鳗科)

First Report of a Mitochondrial Pseudogene in Agnathan Vertebrates (Cyclostomata: Petromyzontidae).

机构信息

Department of Biology, University of Southern Indiana, 8600 University Blvd., Evansville, IN, 47712, USA.

出版信息

J Mol Evol. 2018 Apr;86(3-4):187-189. doi: 10.1007/s00239-018-9835-y. Epub 2018 Mar 21.

DOI:10.1007/s00239-018-9835-y
PMID:29564489
Abstract

We report herein the characterization of a nuclear paralog of a fragment of the mitochondrial genome (a numt) in two closely related species of lampreys (Ichthyomyzon spp.). Although numts have been characterized in several vertebrate taxa, numts have yet to be reported for fishes in general. Given the phylogenetic position of lampreys relative to other vertebrates, the presence of numts within the lamprey genome is either evidence of an ancestral trait lost in other fishes but uniquely retained in agnathans and amniotes, or (more intriguingly) a product of the genome rearrangements these animals undergo during development.

摘要

我们在此报告了在两种密切相关的七鳃鳗(Ichthyomyzon spp.)中,一个线粒体基因组片段(numt)的核同源物的特征。尽管已经在几个脊椎动物分类群中描述了 numt,但一般来说,鱼类的 numt 尚未报道。鉴于七鳃鳗相对于其他脊椎动物的系统发育位置,numt 存在于七鳃鳗基因组中,要么是在其他鱼类中失去的祖先特征的证据,但在无颌类和羊膜动物中独特保留,要么(更有趣的是)是这些动物在发育过程中经历的基因组重排的产物。

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本文引用的文献

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Genetica. 2014 Dec;142(6):545-54. doi: 10.1007/s10709-014-9802-5. Epub 2014 Nov 29.
2
Genetic calibration of species diversity among North America's freshwater fishes.北美淡水鱼类物种多样性的遗传校准。
Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10602-7. doi: 10.1073/pnas.1016437108. Epub 2011 Jun 13.
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Programmed loss of millions of base pairs from a vertebrate genome.
脊椎动物基因组数百万碱基对的程序性缺失。
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Many species in one: DNA barcoding overestimates the number of species when nuclear mitochondrial pseudogenes are coamplified.多种合一:当核线粒体假基因被共同扩增时,DNA条形码会高估物种数量。
Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13486-91. doi: 10.1073/pnas.0803076105. Epub 2008 Aug 29.
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Comparative analysis of mitochondrial fragments transferred to the nucleus in vertebrate.脊椎动物中线粒体片段转移至细胞核的比较分析。
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The lamprey in evolutionary studies.进化研究中的七鳃鳗。
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Molecular analyses of mitochondrial pseudogenes within the nuclear genome of arvicoline rodents.田鼠亚科啮齿动物核基因组中线粒体假基因的分子分析。
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8
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