Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, University of North Carolina at Chapel Hill, 4119B Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC, 27599-7080, USA.
University of Maryland Medical Center, University of Maryland School of Medicine, 22 S Green St, Baltimore, MD, 21201, USA.
Dig Dis Sci. 2018 Jun;63(6):1572-1582. doi: 10.1007/s10620-018-5021-8. Epub 2018 Mar 21.
Aspects of sexual health, which can be adversely affected by chronic disease, have been inadequately explored in inflammatory bowel disease (IBD).
We evaluated patient-reported interest in sexual activity and satisfaction with sex life in a large cohort of IBD patients.
We conducted a cross-sectional study within the Crohn's and Colitis Foundation Partners Internet cohort. Sequential participants completed a 6-question supplemental online survey to examine sexual interest and satisfaction using the Patient-Reported Outcome Measurement Information System (PROMIS) Sexual Function and Satisfaction measures. One-sample t tests were used to compare interest and satisfaction scores to general population norms.
Among 2569 individuals, 1639 had Crohn's disease (CD), 930 had ulcerative colitis (UC) or indeterminate colitis, and 71% were women. Mean PROMIS scores for sexual interest were comparable to the general US population in men (CD: 49 and UC: 50 vs. population mean 50) and women (CD: 41 and UC: 40 vs. population mean 42). However, sexual satisfaction scores were lower than the US population in men (CD: 48 and UC: 48 vs. 51) and women (CD: 47 and UC: 46 vs. 49), p < 0.01 for both. Older age, disease activity, depression, anxiety, and pain were associated with lower interest and satisfaction and lowered IBD-specific quality of life.
IBD patients in a large online survey had similar levels of sexual interest but decreased sexual satisfaction compared to the general population. Exploring these sexual health domains during clinical encounters can aid in improving IBD quality of life.
性健康方面的问题可能会受到慢性疾病的不利影响，但在炎症性肠病（IBD）中，这些方面的问题并未得到充分的研究。
我们评估了在一个大型 IBD 患者队列中，患者对性活动的兴趣和对性生活的满意度。
我们在克罗恩病和结肠炎基金会合作伙伴互联网队列中进行了一项横断面研究。连续的参与者完成了一个 6 个问题的补充在线调查，使用患者报告的结果测量信息系统（PROMIS）性功能和满意度量表来检查性兴趣和满意度。采用单样本 t 检验比较了兴趣和满意度评分与一般人群的正常值。
在 2569 名参与者中，1639 人患有克罗恩病（CD），930 人患有溃疡性结肠炎（UC）或不确定结肠炎，71%为女性。男性 CD（49 分）和 UC（50 分）与 UC（50 分）的一般美国人群相比，男性和女性的 PROMIS 性兴趣平均得分相当（CD：41 分和 UC：40 分）。然而，男性（CD：48 分和 UC：48 分）和女性（CD：47 分和 UC：46 分）的性满意度评分均低于美国人群，两者均<0.01。年龄较大、疾病活动度、抑郁、焦虑和疼痛与较低的兴趣和满意度以及较低的 IBD 特异性生活质量相关。
在一项大型在线调查中，IBD 患者的性兴趣水平与一般人群相似，但性满意度较低。在临床就诊中探讨这些性健康领域可以帮助提高 IBD 的生活质量。
