炎症性肠病中疾病类型和活动度对性生活及生活质量的影响。
The influence of disease type and activity to sexual life and health quality in inflammatory bowel disease.
作者信息
Ateş Bulut Esra, Törüner Murat
机构信息
Department of Geriatric Medicine, Dokuz Eylül University School of Medicine, İzmir, Turkey.
Department of Gastroenterology, Ankara University School of Medicine, Ankara, Turkey.
出版信息
Turk J Gastroenterol. 2019 Jan;30(1):33-39. doi: 10.5152/tjg.2018.18250.
BACKGROUND/AIMS: Inflammatory bowel disease (IBD) has a major impact on patients' quality of life (QoL), mood, and sexual life. The purpose of the present study was to show the effect of disease type and activity on sexual life and QoL in patients with IBD.
MATERIALS AND METHODS
A total of 122 patients with IBD and 42 sex- and age-matched control cases were included in the study. Demographic characteristics were recorded. The disease activity of patients with IBD was assessed by the Harvey-Bradshaw Index in Crohn's disease (CD) and the Mayo Clinical Ulcerative Colitis Activity Index in ulcerative colitis (UC). All participants were subjected to complete three questionnaires: Short Form 36 (SF-36), Hospital Anxiety and Depression Scales (HAD-A and HAD-D), and Arizona Sexual Experience Scale (ASEX).
RESULTS
There was no difference in terms of demographic characteristics between the three groups, except cigarette exposure in CD. The disease activity of patients with UC and CD was not different (p>0.05). The mean HAD-A score was significantly higher in the CD group, whereas the mean HAD-D score was higher in the IBD group than in the control group (p<0.05). Anxiety was seen more frequently in women. SF-36 scale scores were found to be lower in the UC and CD groups than in the control group (p<0.05). The mean ASEX scores of women with UC (19.59±7.59) and CD (19.38±6.27) were both significantly higher than those of the control group (15±4.76). Although the mean ASEX scores of men were not different, some ASEX subscores of the IBD groups were worse than those of the control.
CONCLUSION
Inflammatory bowel disease is a chronic disease that has multiple complications affecting patients' psychosocial life. Patients have more anxiety, depression, and sexual dysfunction when their disease is active. Patients should be screened for psychological diseases and sexual dysfunction, and necessary treatments should be given.
背景/目的：炎症性肠病（IBD）对患者的生活质量（QoL）、情绪和性生活有重大影响。本研究的目的是展示疾病类型和活动度对IBD患者性生活和生活质量的影响。
材料与方法
本研究共纳入122例IBD患者和42例性别及年龄匹配的对照病例。记录人口统计学特征。通过克罗恩病（CD）的哈维-布拉德肖指数和溃疡性结肠炎（UC）的梅奥临床溃疡性结肠炎活动指数评估IBD患者的疾病活动度。所有参与者均完成三份问卷：简短健康调查问卷（SF-36）、医院焦虑抑郁量表（HAD-A和HAD-D）以及亚利桑那性体验量表（ASEX）。
结果
除CD组有吸烟暴露外，三组在人口统计学特征方面无差异。UC组和CD组患者的疾病活动度无差异（p>0.05）。CD组的平均HAD-A评分显著更高，而IBD组的平均HAD-D评分高于对照组（p<0.05）。焦虑在女性中更常见。发现UC组和CD组的SF-36量表评分低于对照组（p<0.05）。UC组（19.59±7.59）和CD组（19.38±6.27）女性的平均ASEX评分均显著高于对照组（15±4.76）。尽管男性的平均ASEX评分无差异，但IBD组的一些ASEX子评分比对照组差。
结论
炎症性肠病是一种慢性疾病，有多种并发症影响患者的心理社会生活。疾病活动时患者有更多焦虑、抑郁和性功能障碍。应对患者进行心理疾病和性功能障碍筛查，并给予必要的治疗。
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