Gómez-Hidalgo Natalia R, Chen Ling, Hou June Y, Tergas Ana I, St Clair Caryn M, Ananth Cande V, Hershman Dawn L, Wright Jason D
a Department of Obstetrics and Gynecology , Columbia University College of Physicians and Surgeons , New York , USA.
d Herbert Irving Comprehensive Cancer Center , Columbia University College of Physicians and Surgeons , New York , New York , USA.
Cancer Invest. 2018 Mar 16;36(3):190-198. doi: 10.1080/07357907.2018.1449212. Epub 2018 Mar 22.
We analyzed 54,039 women with uterine cancer in the National Cancer Database from 2013 to 2014 including 38,453 (71.2%) who underwent lymphadenectomy, 1929 (3.6%) who underwent sentinel lymph node (SLN) mapping, and 13,657 (25.3%) who did not undergo nodal assessment. SLN mapping increased from 2.8% in 2013 to 4.3% in 2014 (P < 0.001). Patients treated in 2014 and those at community centers were more likely to undergo SLN biopsy, while women with advanced-stage disease, sarcomas, and grade 3 tumors were less likely to undergo SLN mapping (P < 0.05). There was no association between use of SLN biopsy and use of radiation (aRR = 0.92; 95% CI, 0.82-1.05).
我们分析了2013年至2014年国家癌症数据库中54039例子宫癌女性患者，其中38453例（71.2%）接受了淋巴结切除术，1929例（3.6%）接受了前哨淋巴结（SLN）定位，13657例（25.3%）未进行淋巴结评估。SLN定位从2013年的2.8%增至2014年的4.3%（P<0.001）。2014年接受治疗的患者以及社区中心的患者更有可能接受SLN活检，而晚期疾病、肉瘤和3级肿瘤的女性接受SLN定位的可能性较小（P<0.05）。SLN活检的使用与放疗的使用之间无关联（aRR=0.92；95%CI，0.82 - 1.05）。
