Jie Xiaoke, Liu Ming, Peng Aidong, Huang Jijun, Zhang Yuanlin, Wang Xuefei, Tian Zhiyuan
School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, Beijing 100049, PR China.
College of Materials Science and Opto-electronic Technology, University of Chinese Academy of Sciences, Beijing 100049, PR China.
Talanta. 2018 Jun 1;183:164-171. doi: 10.1016/j.talanta.2018.02.019. Epub 2018 Feb 9.
A new type of colorimetric, fluorescent palladium (Pd) probe characterized with beaconing fluorescence signal in the quiet near-infrared (NIR) region (centered ~ 717 nm), recognition response time of approximately 3 min, limit of detection (LOD) down to 5.1 ppb, and excellent recognition specificity over a wide range of interfering metal cations was developed. It is believed that the probe underwent sequential Pd-mediated oxidative addition and reduction elimination reactions, yielding typical D-π-A molecular skeleton of the final reaction product capable of intramolecular charge transfer (ICT). The benzothiazole moiety of the probe molecular skeleton is believed to play a vital trole in shifting the beaconing fluorescence signal to the quiet NIR region and accelerating the Pd recognition process of the probe via the formation of the fluorescent reaction product with largely extended π-delocalization. With unique advantages, the fluorescent probe we developed will find practical applications for detecting residual Pd with concentration below the safety margin in pharmacy and biomedical engineering.
开发了一种新型比色荧光钯（Pd）探针，其在安静的近红外（NIR）区域（中心波长约717 nm）具有信标荧光信号，识别响应时间约为3分钟，检测限（LOD）低至5.1 ppb，并且在广泛的干扰金属阳离子范围内具有出色的识别特异性。据信，该探针经历了连续的钯介导的氧化加成和还原消除反应，产生了能够进行分子内电荷转移（ICT）的最终反应产物的典型D-π-A分子骨架。据信，探针分子骨架的苯并噻唑部分在将信标荧光信号转移到安静的近红外区域以及通过形成具有大大扩展的π离域的荧光反应产物来加速探针的钯识别过程中起着至关重要的作用。我们开发的荧光探针具有独特的优势，将在检测药学和生物医学工程中浓度低于安全边际的残留钯方面找到实际应用。
