King Jeanmari, Hagemeister Dirk T
Division of Family Medicine and Primary Care, Stellenbosch University, South Africa.
District Health Services, Western Cape Department of Health, South Africa.
South Afr J HIV Med. 2016 May 20;17(1):336. doi: 10.4102/sajhivmed.v17i1.336. eCollection 2016.
Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) co-infection in South Africa is estimated to be between 5% and 23%; however, only limited evidence is available. Co-infection increases the risk of chronification of HBV, liver cirrhosis and death.
To assess the HBV and/or HIV co-infection rate amongst the adult antiretroviral treatment cohort at the TC Newman ART Clinic in Paarl, Western Cape.
In a retrospective, cross-sectional study, the routine hepatitis B surface antigen screening results for all adult HIV patients who were started on antiretroviral treatment over a period of 19 months were collected and analysed for gender, CD4 count and age.
Amongst the 498 participants (60% female participants), the Hepatitis B surface Antigen positivity rate was 7.6%. Male gender, age between 50 and 59 years and a low CD4 count were correlated with higher rates.
Useful insight could be obtained by analysing routine data. The prevalence of almost 8% confirms the need for testing of HIV-positive patients for hepatitis B.
据估计，南非乙肝病毒（HBV）与人类免疫缺陷病毒（HIV）合并感染率在5%至23%之间；然而，现有证据有限。合并感染会增加HBV慢性化、肝硬化和死亡风险。
评估西开普省帕尔市TC纽曼抗逆转录病毒治疗诊所成年抗逆转录病毒治疗队列中的HBV和/或HIV合并感染率。
在一项回顾性横断面研究中，收集了19个月期间开始接受抗逆转录病毒治疗的所有成年HIV患者的常规乙肝表面抗原筛查结果，并对性别、CD4细胞计数和年龄进行了分析。
在498名参与者中（60%为女性参与者），乙肝表面抗原阳性率为7.6%。男性、年龄在50至59岁之间以及CD4细胞计数低与较高的感染率相关。
通过分析常规数据可获得有用见解。近8%的患病率证实了对HIV阳性患者进行乙肝检测的必要性。
