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妊娠期间高血糖环境的变化:妊娠期糖尿病和妊娠糖尿病。

Changing environment of hyperglycemia in pregnancy: Gestational diabetes and diabetes mellitus in pregnancy.

机构信息

School of Pharmacy, The University of Queensland, Woolloongabba, Queensland, Australia.

Department of Endocrinology, Royal Prince Alfred Hospital, Boden Institute and Central Clinical School, University of Sydney, Sydney, New South Wales, Australia.

出版信息

J Diabetes. 2018 Aug;10(8):633-640. doi: 10.1111/1753-0407.12660. Epub 2018 Apr 26.

Abstract

The diagnosis and treatment of gestational diabetes mellitus (GDM) have been in a state of flux since the World Health Organization accepted and endorsed the International Diabetes and Pregnancy Study Group's diagnostic pathway and criteria in 2013. These new diagnostic criteria identify an increasing number of women at risk of hyperglycemia in pregnancy (HGiP). Maternal hyperglycemia represents a significant risk to the mother and fetus, in both the short and long term. Controversially, metformin use for the treatment of GDM is increasing in Australia. This article identifies the multiple and varied presentations of HGiP, of which GDM is the most commonly encountered. The degree of maternal hyperglycemia experienced affects the outcomes for both the mother and neonate, and specific diagnosis determines the appropriate treatment for the pregnancy. Given the increasing incidence of women with dysglycemia and those developing HGiP, this is an important area for research and clinical attention for all health professionals.

摘要

自 2013 年世界卫生组织接受并认可国际糖尿病与妊娠研究组的诊断途径和标准以来,妊娠期糖尿病(GDM)的诊断和治疗一直处于不断变化的状态。这些新的诊断标准确定了越来越多的孕妇有妊娠高血糖(HGiP)的风险。孕妇的高血糖对母亲和胎儿都有短期和长期的重大风险。有争议的是,二甲双胍在澳大利亚用于治疗 GDM 的使用正在增加。本文确定了 HGiP 的多种不同表现形式,其中 GDM 是最常见的。母亲经历的高血糖程度会影响母亲和新生儿的结局,具体的诊断确定了妊娠的适当治疗方法。鉴于患有血糖异常和发生 HGiP 的女性人数不断增加,这是所有卫生专业人员都需要关注的一个重要研究领域。

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