Goodman D S, Teplitz E D, Wishner A, Klein R S, Burk P G, Hershenbaum E
J Am Acad Dermatol. 1987 Aug;17(2 Pt 1):210-20. doi: 10.1016/s0190-9622(87)70193-5.
Ninety adult patients with acquired immunodeficiency syndrome (AIDS) and 27 with AIDS-related complex were seen consecutively, when available, either as inpatients or in AIDS clinics and given complete cutaneous examinations. Skin disease was common both in patients with AIDS and in those with AIDS-related complex. The most common cutaneous findings were candidiasis in 55 patients (47.0%), dermatophytosis in 35 (30%), herpes simplex infections in 26 (22%), molluscum contagiosum in 11 (9%), seborrheic dermatitis in 37 (32%), and acquired ichthyosis or xerosis in 36 (30%). Several cutaneous conditions previously reported in association with AIDS were infrequently seen: Psoriasis was seen in only one patient, and deep fungal infections and basal and squamous cell carcinomas were seen in none. No significant differences were noted in the prevalence of skin disease between patients with AIDS and those with AIDS-related complex, although xerosis and ichthyosiform skin changes tended to be more common in those with AIDS. The yellow nail syndrome and "a papular eruption" associated with AIDS were seen. Skin diseases also tended to be widespread and severe in the patients studied.
对90例获得性免疫缺陷综合征（AIDS）成年患者和27例艾滋病相关综合征患者进行了连续观察，如有可能，他们作为住院患者或在艾滋病诊所接受了完整的皮肤检查。皮肤疾病在艾滋病患者和艾滋病相关综合征患者中都很常见。最常见的皮肤表现为念珠菌病55例（47.0%）、皮肤癣菌病35例（30%）、单纯疱疹感染26例（22%）、传染性软疣11例（9%）、脂溢性皮炎37例（32%）、获得性鱼鳞病或皮肤干燥症36例（30%）。先前报道的几种与艾滋病相关的皮肤疾病很少见：仅1例患者出现银屑病，未见深部真菌感染以及基底细胞癌和鳞状细胞癌。艾滋病患者和艾滋病相关综合征患者之间的皮肤疾病患病率无显著差异，尽管皮肤干燥症和鱼鳞病样皮肤改变在艾滋病患者中更常见。观察到了与艾滋病相关的黄甲综合征和“丘疹性皮疹”。在所研究的患者中，皮肤疾病也往往广泛且严重。
