State Key Laboratory of Crop Biology, College of Life Sciences, College of Forestry, Shandong Agricultural University, Taian, Shandong, 271018, China.
New Phytol. 2018 Jun;218(4):1334-1339. doi: 10.1111/nph.15106. Epub 2018 Mar 25.
Contents Summary 1334 I. Introduction 1334 II. Regeneration-initial cell: the origin of regeneration 1335 III. Acquiring regeneration competency: the essential intermediate step for hormone-induced regeneration 1335 IV. Hormonal induction of stem cell regulators: the program for de novo establishment of apical meristems 1337 V. Conclusions and perspectives 1337 Acknowledgements 1338 Author contributions 1338 References 1338 SUMMARY: High cellular plasticity confers remarkable regeneration capacity to plants. Based on the activity of stem cells and their regulators, higher plants are capable of regenerating new individuals. De novo organogenesis exemplifies the regeneration of the whole plant body and is exploited widely in agriculture and biotechnology. In this Tansley insight article, we summarize recent advances that facilitate our understanding of the molecular mechanisms underlying de novo organogenesis. According to our current knowledge, this process can be divided into three steps, including activation of regeneration-initial cells, acquisition of competency and de novo establishment of apical meristems. The functions of stem cells and their regulators are critical to de novo organogenesis, whereas auxin and cytokinin act as triggers and linkers between different steps.
内容概要 1334 I. 引言 1334 II. 再生起始细胞：再生的起源 1335 III. 获得再生能力：激素诱导再生的必要中间步骤 1335 IV. 激素诱导干细胞调控因子：从头建立顶端分生组织的程序 1337 V. 结论和展望 1337 致谢 1338 作者贡献 1338 参考文献 1338 概要：高细胞可塑性赋予植物显著的再生能力。基于干细胞及其调控因子的活性，高等植物能够再生新的个体。从头器官发生是植物整体再生的典范，在农业和生物技术中得到了广泛的应用。在这篇 Tansley 观点文章中，我们总结了促进我们理解从头器官发生分子机制的最新进展。根据我们目前的知识，这个过程可以分为三个步骤，包括再生起始细胞的激活、获得再生能力和从头建立顶端分生组织。干细胞及其调控因子的功能对从头器官发生至关重要，而生长素和细胞分裂素则作为不同步骤之间的触发和连接物。
