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Diuretic dosing in heart failure: more data are needed.

作者信息

De Vecchis Renato, Rigopoulos Angelos, Bigalke Boris, Manginas Athanassios, Tschöpe Carsten, Noutsias Michel

机构信息

Cardiology Unit, Presidio Sanitario Intermedio "Elena d'Aosta", via Cagnazzi 29, c.a.p, 80137, Napoli, Italy.

Department of Internal Medicine III, Division of Cardiology, Angiology and Intensive Medical Care, University Hospital Halle, Martin-Luther-University Halle, Ernst-Grube-Straße 40, D-06120, Halle (Saale), Germany.

出版信息

ESC Heart Fail. 2018 Aug;5(4):649-650. doi: 10.1002/ehf2.12229. Epub 2018 Mar 25.

DOI:10.1002/ehf2.12229
PMID:29575802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6073013/
Abstract
摘要

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Diuretic dosing in heart failure: more data are needed.心力衰竭中的利尿剂给药：需要更多数据。
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In chronic heart failure with marked fluid retention, the i.v. high doses of loop diuretic are a predictor of aggravated renal dysfunction, especially in the set of heart failure with normal or only mildly impaired left ventricular systolic function.在伴有明显液体潴留的慢性心力衰竭中，静脉注射大剂量袢利尿剂是肾功能恶化的一个预测指标，尤其是在左心室收缩功能正常或仅轻度受损的心力衰竭患者中。
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引用本文的文献

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Eur Heart J Suppl. 2019 Feb;21(Suppl A):A41-A47. doi: 10.1093/eurheartj/suy031. Epub 2019 Feb 26.

本文引用的文献

1
The association between high-dose loop diuretic use at discharge and cardiovascular mortality in patients with heart failure.出院时大剂量使用袢利尿剂与心力衰竭患者心血管死亡率的关系。
ESC Heart Fail. 2018 Feb;5(1):87-94. doi: 10.1002/ehf2.12221. Epub 2017 Oct 2.
2
The Efficacy and Safety of Tolvaptan in Patients with Hyponatremia: A Meta-Analysis of Randomized Controlled Trials.托伐普坦治疗低钠血症患者的疗效与安全性：随机对照试验的荟萃分析
Clin Drug Investig. 2017 Apr;37(4):327-342. doi: 10.1007/s40261-016-0470-3.
3
Diuretic Use and Risk of Vertebral Fracture in Women.女性利尿剂的使用与椎体骨折风险
Am J Med. 2016 Dec;129(12):1299-1306. doi: 10.1016/j.amjmed.2016.07.013. Epub 2016 Aug 16.
4
In right or biventricular chronic heart failure addition of thiazides to loop diuretics to achieve a sequential blockade of the nephron is associated with increased risk of dilutional hyponatremia: results of a case-control study.在右心或双心室慢性心力衰竭中，将噻嗪类药物添加到袢利尿剂中以实现对肾单位的序贯阻断，与稀释性低钠血症风险增加相关：一项病例对照研究的结果。
Minerva Cardioangiol. 2012 Oct;60(5):517-29.
5
Impact of dopamine infusion on renal function in hospitalized heart failure patients: results of the Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial.多巴胺输注对住院心力衰竭患者肾功能的影响：急性失代偿性心力衰竭（DAD-HF）试验的结果。
J Card Fail. 2010 Dec;16(12):922-30. doi: 10.1016/j.cardfail.2010.07.246.
6
Contemporary trends in the pharmacological and extracorporeal management of heart failure: a nephrologic perspective.心力衰竭的药物和体外管理的当代趋势：肾脏学视角
Circulation. 2008 Feb 19;117(7):975-83. doi: 10.1161/CIRCULATIONAHA.107.742270.