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女性可改变的生活方式因素与卵巢癌发病率

Modifiable lifestyle factors and ovarian cancer incidence in women.

作者信息

Plagens-Rotman Katarzyna, Chmaj-Wierzchowska Karolina, Pięta Beata, Bojar Iwona

机构信息

Department of Mother's and Child's Health, University of Medical Sciences, Poznań, Poland.

Department for Woman Health, Institute of Rural Health in Lublin, Poland.

出版信息

Ann Agric Environ Med. 2018 Mar 14;25(1):36-40. doi: 10.5604/12321966.1233565. Epub 2017 May 11.

DOI:10.5604/12321966.1233565
PMID:29575880
Abstract

INTRODUCTION

A correct diet plays an important role in the prevention of malignant tumours. The risk of the disease may be reduced by introducing a number of changes to the daily diet. The most important changes concern the amount of fat in the diet, dietary fibre, antioxidants in the food and the reduction of substances having a significant impact on the development of malignant tumours.

OBJECTIVE

The aim of the study is to analyse the role of selected modifiable lifestyle factors affecting the development of ovarian cancer.

MATERIAL AND METHODS

The study covered healthy women and women with diagnosed ovarian cancer. A total of 850 women aged between 21-84 were studied. The study included women visiting the Gynaecology and Obstetrics Hospital of the University of Medical Sciences in Poznan, Poland, between 2011-2013. Patients recognized with malignant ovarian cancer were qualified into the study based on the histopathological examination of the material obtained during surgery.

RESULTS

Respondents who consumed fruit and vegetables several times a week have the odds ratio OR = 0.29 level; 95% CI 0.04-2.01 (p =.2085), compared to women not consuming fruit and vegetables at all. Consumption of 100 g of French fries and potato chips several times a week, results in a 2-fold increase in ovarian cancer. The OR for this group of women amounts to 2.06; 95% CI 0.53-7.99 (p=.2966).

CONCLUSIONS

A diet rich in fruit and vegetables, including bulb vegetables, and grain products containing whole grains, should be introduced. It is recommended that the consumption of popular fast foods be eliminated.

摘要

引言

正确的饮食在预防恶性肿瘤方面起着重要作用。通过对日常饮食进行一些改变,可降低患这种疾病的风险。最重要的改变涉及饮食中的脂肪量、膳食纤维、食物中的抗氧化剂以及减少对恶性肿瘤发展有重大影响的物质。

目的

本研究的目的是分析某些可改变的生活方式因素对卵巢癌发展的作用。

材料与方法

该研究涵盖了健康女性和已确诊卵巢癌的女性。总共研究了850名年龄在21 - 84岁之间的女性。研究对象包括2011年至2013年期间前往波兰波兹南医科大学妇产科医院就诊的女性。经手术获取的材料经组织病理学检查确诊为恶性卵巢癌的患者被纳入研究。

结果

与完全不食用水果和蔬菜的女性相比,每周食用几次水果和蔬菜的受访者的优势比OR = 0.29;95%置信区间为0.04 - 2.01(p = 0.2085)。每周食用几次100克炸薯条和薯片会使卵巢癌风险增加两倍。该组女性的OR为2.06;95%置信区间为0.53 - 7.99(p = 0.2966)。

结论

应采用富含水果和蔬菜(包括球茎类蔬菜)以及含有全谷物的谷物产品的饮食。建议杜绝食用常见的快餐食品。

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