Ishikawa Sho, Kato Naoko
Department of Ophthalmology, Saitama Medical University, Saitama, Japan.
Am J Ophthalmol Case Rep. 2018 Jan 12;9:116-118. doi: 10.1016/j.ajoc.2018.01.004. eCollection 2018 Mar.
To report a case with corneal perforation, presumably due to ocular cicatricial pemphigoid (OCP) and bacterial concretion derived from lacrimal canaliculitis.
A patient with OCP demonstrated adherence of concretion to the cornea of her right eye. She also demonstrated canaliculitis in this eye. We removed a whitish precipitate from the bottom of the corneal ulcer. When we flushed her lacrimal pathway, a marked amount of bacterial concretion and dense mucosa were refluxed from both puncta on the right side. On the next day, corneal perforation was visible from the area where concretion was removed. We performed punctoplasty and removed the bacterial concretion from the lacrimal canaliculus and sac. After the operation, her symptoms improved and corneal perforation recovered.
Both lacrimal canaliculitis and OCP can cause corneal perforation, and adherence of bacterial concretion onto the cornea is very rare. However, once it occurs, corneal perforation can rapidly follow. OCP sometimes causes corneal epithelial damage, which may influence adherence to concretion. Canaliculitis in patients with OCP should be managed carefully.
报告一例角膜穿孔病例,推测病因是瘢痕性类天疱疮(OCP)和源自泪小管炎的细菌性结石。
一名患有OCP的患者表现出结石附着于右眼角膜。她的这只眼睛还存在泪小管炎。我们从角膜溃疡底部取出了白色沉淀物。当冲洗她的泪道时,大量的细菌性结石和致密的黏膜从右侧的两个泪点反流出来。第二天,在取出结石的区域可见角膜穿孔。我们进行了泪点成形术,并从泪小管和泪囊中取出了细菌性结石。术后,她的症状有所改善,角膜穿孔也得以恢复。
泪小管炎和OCP均可导致角膜穿孔,细菌性结石附着于角膜的情况非常罕见。然而,一旦发生,角膜穿孔可能会迅速出现。OCP有时会导致角膜上皮损伤,这可能会影响结石的附着。对于患有OCP的患者的泪小管炎应谨慎处理。