Nakajima Kei, Kanda Eiichiro, Suwa Kaname
School of Nutrition and Dietetics, Faculty of Health and Social Services, Kanagawa University of Human Services, 1-10-1 Heisei-cho, Yokosuka, Kanagawa, 238-8522, Japan.
Department of Nephrology, Tokyo Kyosai Hospital, Meguro, Tokyo, Japan.
BMC Res Notes. 2018 Mar 27;11(1):195. doi: 10.1186/s13104-018-3315-8.
Hearing loss may be associated with certain sleep abnormalities. We recently reported that subclinical hearing loss (SHL) was more prevalent in individuals in a broad Japanese population who slept longer than 8 h; however, the underlying mechanism was unknown. Therefore, we investigated the association between SHL and self-reported restorative sleep (RS), assessed by questionnaire, in a database of 33,888 Japanese aged 40-69 years without overt or diagnosed hearing loss (20,225 men, 13,663 women).
The proportion of individuals with RS (more than half of the subjects) was significantly higher in the group with bilateral than with unilateral SHL at 4000 Hz and intact hearing; however, that was not the case at 1000 Hz, independent of age (P < 0.0001, two-way analysis of variance). Multivariate logistic regression analysis showed that bilateral SHL at 4000 Hz, but not at 1000 Hz, was significantly associated with RS. This relationship was independent of potential relevant confounders, including age, sex, and cardiometabolic risk factors. The present study extends our earlier work by revealing an unexpected association between early hearing impairment and satisfactory sleep in a middle-aged and elderly population. This association requires further confirmation regarding the possible underlying mechanism and clinical relevance.
听力损失可能与某些睡眠异常有关。我们最近报告称,在睡眠时间超过8小时的广大日本人群中,亚临床听力损失(SHL)更为普遍;然而,其潜在机制尚不清楚。因此,我们在一个包含33888名年龄在40 - 69岁、无明显或已确诊听力损失的日本人的数据库(20225名男性,13663名女性)中,通过问卷调查评估,研究了SHL与自我报告的恢复性睡眠(RS)之间的关联。
在4000Hz频率且听力正常的情况下,双侧SHL组中具有RS(超过半数受试者)的个体比例显著高于单侧SHL组;然而,在1000Hz频率时并非如此,且与年龄无关(P < 0.0001,双向方差分析)。多因素逻辑回归分析表明,4000Hz频率的双侧SHL与RS显著相关,但1000Hz频率时并非如此。这种关系独立于潜在的相关混杂因素,包括年龄、性别和心血管代谢危险因素。本研究通过揭示中年和老年人群中早期听力障碍与良好睡眠之间意想不到的关联,扩展了我们早期的工作。这种关联的潜在机制和临床相关性需要进一步证实。