Department of Radiation Oncology, Stanford University, Stanford, CA.
Department of Radiation Oncology, Stanford University, Stanford, CA.
Semin Oncol. 2017 Oct;44(5):310-322. doi: 10.1053/j.seminoncol.2018.01.008. Epub 2018 Feb 3.
Appropriate post-treatment management of patients with lymphoma has been controversial, with imaging frequently performed as post-treatment surveillance. The goal of post-treatment imaging is to identify relapse prior to clinical symptoms, when the burden of disease is lower and the possibility of effective salvage therapy and cure are greater. However, little data exist to support the performance of surveillance imaging after completion of treatment, with the vast majority of studies suggesting there is no clinical benefit to surveillance imaging in asymptomatic patients. Ongoing efforts seek to identify a subset of patients with a higher risk of relapse that might benefit from surveillance imaging, though financial and other costs associated with imaging are non-negligible and must be considered. Here we summarize the current data regarding post-treatment surveillance imaging in lymphoma.
淋巴瘤患者的适当治疗后管理一直存在争议,常采用影像学检查作为治疗后监测手段。治疗后影像学检查的目的是在出现临床症状之前发现复发,此时疾病负担较低,有效挽救治疗和治愈的可能性更大。然而,目前几乎没有数据支持治疗完成后进行监测性影像学检查,绝大多数研究表明,在无症状患者中,监测性影像学检查没有临床获益。目前正在努力确定一组复发风险较高的患者,这些患者可能受益于监测性影像学检查,但影像学检查相关的经济和其他成本不可忽视,必须加以考虑。本文总结了目前淋巴瘤治疗后监测性影像学检查的相关数据。