Bovonsunthonchai Sunee, Witthiwej Theerapol, Ngamsombat Chanon, Sathornsumetee Sith, Vachalathiti Roongtiwa, Muangpaisan Weerasak, Hengsomboon Pichaya, Thong-On Suthasinee, Jankhum Supattra, Yangyoo Pusanisa
Faculty of Physical Therapy, Mahidol University, Nakhon Pathom, Thailand.
Division of Neurosurgery, Department of Surgery, Mahidol University, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand.
Nagoya J Med Sci. 2018 Feb;80(1):53-60. doi: 10.18999/nagjms.80.1.53.
The aim of the study was to investigate the effect of the spinal tap test on sit-to-stand (STS), walking, and turning and to determine the relationship among the outcome measures of STS, walking, and turning in patients with iNPH. Twenty-seven patients with clinical symptoms of iNPH were objectively examined for STS, walking, and turning by the Force Distribution Measurement (FDM) platform connected with a video camera. Assessments were performed at before and 24 hours after spinal tap. Motor abilities were assessed by the STS time, time of walking over 3 meters, and time and number of steps when turning over 180 degrees. Significant improvements were found in the STS time (p = 0.046), walking time (p = 0.048), and turning step (p = 0.001). In addition, turning time was improved but not statistically significant (p = 0.064). Significant relationships were found among all outcome measures (p < 0.001). The relationship among these outcome measures indicated that the individuals had similar ability levels to perform different activities. This may serve as a new choice of outcome measures to evaluate the effect of intervention in different severity levels of patients with iNPH.
本研究的目的是调查腰椎穿刺试验对从坐到站(STS)、行走和转身的影响,并确定特发性正常压力脑积水(iNPH)患者中STS、行走和转身的结果测量之间的关系。27例有iNPH临床症状的患者通过与摄像机相连的力分布测量(FDM)平台对STS、行走和转身进行了客观检查。在腰椎穿刺前和穿刺后24小时进行评估。通过STS时间、3米以上行走时间以及180度转身时的时间和步数来评估运动能力。发现STS时间(p = 0.046)、行走时间(p = 0.048)和转身步数(p = 0.001)有显著改善。此外,转身时间有所改善,但无统计学意义(p = 0.064)。在所有结果测量之间发现了显著的相关性(p < 0.001)。这些结果测量之间的关系表明个体在进行不同活动时有相似的能力水平。这可能作为一种新的结果测量选择,用于评估不同严重程度的iNPH患者的干预效果。