Metabiota DRC, Kinshasa, DR Congo.
School of Public Health, Kinshasa, DR Congo.
J Gen Virol. 2018 May;99(5):676-681. doi: 10.1099/jgv.0.001048. Epub 2018 Mar 27.
Bocaparvoviruses are members of the family Parvovirinae and human bocaviruses have been found to be associated with respiratory and gastrointestinal disease. There are four known human bocaviruses, as well as several distinct ones in great apes. The goal of the presented study was to detect other non-human primate (NHP) bocaviruses in NHP species in the Democratic Republic of the Congo using conventional broad-range PCR. We found bocavirus DNA in blood and tissues samples in 6 out of 620 NHPs, and all isolates showed very high identity (>97 %) with human bocaviruses 2 or 3. These findings suggest cross-species transmission of bocaviruses between humans and NHPs.
杯状病毒是细小病毒科的成员，人类杯状病毒已被发现与呼吸道和胃肠道疾病有关。目前已知有四种人类杯状病毒，以及在大型类人猿中存在几种不同的病毒。本研究的目的是使用常规广谱 PCR 检测刚果民主共和国的灵长类动物（NHP）物种中的其他非人类灵长类动物（NHP）杯状病毒。我们在 620 只 NHP 的血液和组织样本中发现了 6 只杯状病毒 DNA，所有分离株与人杯状病毒 2 或 3 的同源性非常高（>97%）。这些发现表明杯状病毒在人类和 NHP 之间存在跨物种传播。
