Yoo Myung Hoon, Cho Yang-Sun, Choi June, Choung Yun Hoon, Chung Jae-Ho, Chung Jong Woo, Han Gyu Cheol, Jeon Eun-Ju, Jun Beom Cho, Kim Dong-Kee, Kim Kyu Sung, Lee Jun Ho, Lee Kyu-Yup, Lee Seung Hwan, Moon In Seok, Park Hong Ju, Park Shi Nae, Rhee Jihye, Seo Jae Hyun, Yeo Seung Geun
Department of Otorhinolaryngology-Head and Neck Surgery, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2018 Sep;11(3):181-185. doi: 10.21053/ceo.2017.01473. Epub 2018 Mar 28.
The aim of this multicenter registry study was to investigate the effectiveness of ventilation tube insertion and the microbiology of otitis media with effusion (OME) in children. This part I study was conducted to evaluate the microbiological profile of children with OME who needed ventilation tube insertion.
Patients <15 years old who were diagnosed as having OME and received ventilation tube insertion were prospectively enrolled in 16 tertiary hospitals from June 2014 to December 2016. After excluding patients with missing data, the data of 397 patients were analyzed among a total of 433 enrolled patients. The clinical symptoms, findings of the tympanic membrane, hearing level, and microbiological findings were collected.
In 103 patients (25.9%), antibiotics were used within 3 weeks before surgery. Ventilation tube insertion was performed in a total of 710 ears (626 in both ears in 313 patients, 55 in the left ear only, and 29 in the right ear only). Culture of middle ear effusion was done in at least one ear in 221 patients (55.7%), and in a total of 346 ears. Only 46 ears (13.3%) showed positive results in middle ear effusion culture. (17.3%, followed by coagulase-negative and ) was the most common bacteria detected.
was the most commonly found bacteria in middle ear effusion. Relatively low rates of culture positivity were noted in middle ear effusion of patients with OME in Korea.
这项多中心注册研究的目的是调查儿童置管通气的有效性以及分泌性中耳炎（OME）的微生物学情况。本研究的第一部分旨在评估需要置管通气的OME患儿的微生物学特征。
2014年6月至2016年12月，前瞻性纳入16家三级医院中年龄＜15岁、被诊断为OME并接受置管通气的患者。在排除数据缺失的患者后，对总共433名入组患者中的397例患者的数据进行了分析。收集了临床症状、鼓膜检查结果、听力水平和微生物学检查结果。
103例患者（25.9%）在手术前3周内使用了抗生素。总共710只耳朵进行了置管通气（313例患者双耳置管626只，仅左耳置管55只，仅右耳置管29只）。221例患者（55.7%）至少一只耳朵进行了中耳积液培养，总共346只耳朵。中耳积液培养仅46只耳朵（13.3%）呈阳性结果。（17.3%，其次是凝固酶阴性和）是检测到的最常见细菌。
是中耳积液中最常见的细菌。韩国OME患者中耳积液培养阳性率相对较低。
