Risør Bettina Wulff, Lisby Marianne, Sørensen Jan
Department of Public Health, Centre for Health Economics Research (COHERE), University of Southern Denmark, J.B. Winsløwsvej 9B, Odense C, Denmark.
Hospital Pharmacy, Central Denmark Region, Noerrebrogade 44, Aarhus C, Denmark.
Int J Qual Health Care. 2018 Jul 1;30(6):457-465. doi: 10.1093/intqhc/mzy042.
The objective of this study was to evaluate the effectiveness of two automated medication systems in reducing medication administration errors.
The study was a controlled before-and-after study and included three observation periods with collection of data during a 3-week period as initial baseline and two subsequent follow-up periods at 10 and 20 months.
The study was conducted in two Danish acute medical units.
Two automated medication systems were implemented: (i) a complex automated medication system (cAMS) consisting of an automated dispensing cabinet, automated unit-dose dispensing and barcode medication administration (BCMA) and (ii) a non-patient-specific automated medication system (npsAMS) consisting of automated unit-dose dispensing and BCMA.
The occurrence of administration errors and sub-types; procedural and clinical errors were observed. The proportion of errors was calculated by dividing the number of doses with one or more errors with the number of opportunities for errors. Difference-in-difference analysis using logistic regression was used to assess changes in proportion of errors.
Compared with control, the cAMS reduced the overall risk of administration errors in the intervention unit, (odds ratio (OR) 0.53; 95% confidence interval (CI) 0.27-0.90) and procedural errors were significantly reduced as well (OR 0.44; 95% CI 0.126-0.94). The npsAMS effectively reduced the clinical errors in the intervention ward (OR 0.38; 95% CI 0.15-0.96).
In line with previous research, this study found that technological interventions in the medication administration process could reduce the occurrence of medication errors.
本研究的目的是评估两种自动化给药系统在减少给药错误方面的有效性。
该研究为对照前后研究,包括三个观察期,在3周内收集数据作为初始基线,并在10个月和20个月后进行两个后续随访期。
该研究在丹麦的两个急性医疗单位进行。
实施了两种自动化给药系统:(i)一种复杂的自动化给药系统(cAMS),包括自动配药柜、自动单剂量配药和条形码给药(BCMA);(ii)一种非患者特定的自动化给药系统(npsAMS),包括自动单剂量配药和BCMA。
观察给药错误及其亚型的发生情况;程序错误和临床错误。错误比例通过将有一个或多个错误的剂量数除以错误机会数来计算。使用逻辑回归的差异分析来评估错误比例的变化。
与对照组相比,cAMS降低了干预科室给药错误的总体风险(优势比(OR)0.53;95%置信区间(CI)0.27 - 0.90),程序错误也显著降低(OR 0.44;95% CI 0.126 - 0.94)。npsAMS有效降低了干预病房的临床错误(OR 0.38;95% CI 0.15 - 0.96)。
与先前的研究一致,本研究发现给药过程中的技术干预可以减少用药错误的发生。