Department of Women's and Children's Health, University of Otago, Dunedin, New Zealand.
School of Psychology, Flinders University, Adelaide, Australia.
Sleep. 2018 Apr 1;41(4). doi: 10.1093/sleep/zsy017.
Despite the widespread use of actigraphy in pediatric sleep studies, there are currently no age-related normative data.
To systematically review the literature, calculate pooled mean estimates of actigraphy-derived pediatric nighttime sleep variables and to examine the magnitude of change with age.
A systematic search was performed across eight databases of studies that included at least one actigraphy sleep variable from healthy children aged 0-18 years. Data suitable for meta-analysis were confined to ages 3-18 years with seven actigraphy variables analyzed using random effects meta-analysis and meta-regression performed using age as a covariate.
In total, 1334 articles did not meet inclusion criteria; 87 had data suitable for review and 79 were suitable for meta-analysis. Pooled mean estimates for overnight sleep duration declined from 9.68 hours (3-5 years age band) to 8.98, 8.85, 8.05, and 7.4 for age bands 6-8, 9-11, 12-14, and 15-18 years, respectively. For continuous data, the best-fit (R2 = 0.74) equation for hours over the 0-18 years age range was 9.02 - 1.04 × [(age/10)^2 - 0.83]. There was a significant curvilinear association between both sleep onset and offset with age (p < .001). Sleep latency was stable at 19.4 min per night. There were significant differences among the older age groups between weekday and weekend/nonschool days (18 studies). Total sleep time in 15-18 years old was 56 min longer, and sleep onset and offset almost 1 and 2 hours later, respectively, on weekend or nonschool days.
These normative values have potential application to assist the interpretation of actigraphy measures from nighttime recordings across the pediatric age range, and aid future research.
尽管在儿科睡眠研究中广泛使用活动记录仪，但目前尚无与年龄相关的规范数据。
系统回顾文献，计算活动记录仪得出的儿科夜间睡眠变量的汇总均值估计值，并研究其随年龄变化的幅度。
在八个数据库中进行了系统搜索，这些数据库包含了至少一个来自 0-18 岁健康儿童的活动记录仪睡眠变量的研究。适合进行荟萃分析的数据仅限于 3-18 岁年龄组，使用随机效应荟萃分析分析了七个活动记录仪变量，并使用年龄作为协变量进行荟萃回归。
共有 1334 篇文章不符合纳入标准；87 篇有适合审查的数据，79 篇适合荟萃分析。夜间睡眠时间的汇总均值估计值从 3-5 岁年龄组的 9.68 小时下降到 6-8 岁、9-11 岁、12-14 岁和 15-18 岁年龄组的 8.98、8.85、8.05 和 7.4 小时。对于连续数据，0-18 岁年龄范围的最佳拟合（R2=0.74）方程为 9.02-1.04×[(age/10)^2-0.83]。睡眠起始和结束时间与年龄之间存在显著的曲线关系（p<.001）。睡眠潜伏期每晚稳定在 19.4 分钟。在较年长的年龄组中，工作日和周末/非上学日之间存在显著差异（18 项研究）。15-18 岁的总睡眠时间长 56 分钟，入睡和醒来时间分别晚 1 小时和 2 小时。
这些规范值可用于协助解释儿科年龄范围内的夜间记录的活动记录仪测量值，并有助于未来的研究。
