雏鸡从胚胎营养环境过渡到新生营养环境过程中肝脏果糖-2,6-二磷酸含量和磷酸果糖激酶-1活性的发育变化。
Developmental changes in hepatic fructose 2,6-bisphosphate content and phosphofructokinase-1 activity in the transition of chicks from embryonic to neonatal nutritional environment.
作者信息
Hamer M J, Dickson A J
机构信息
Department of Biochemistry and Molecular Biology, University of Manchester, U.K.
出版信息
Biochem J. 1987 Jul 1;245(1):35-9. doi: 10.1042/bj2450035.
Abstract
Within 2 days of hatching in chicks, there are parallel increases in hepatic fructose 2,6-bisphosphate content and phosphofructokinase-1 activity. The changes observed are a consequence of feeding on the carbohydrate-rich diet of neonatal life: lack of access to food after hatching prevents changes for either parameter. The results are discussed in relation to changes in the activities of hepatic lipogenic enzymes during the embryonic/neonatal transition of chicks and the role of insulin in co-ordination of developmental processes.
摘要
在雏鸡孵化后的2天内，肝脏中果糖2,6 - 二磷酸的含量和磷酸果糖激酶-1的活性同时增加。观察到的这些变化是雏鸡新生期以富含碳水化合物的食物为食的结果：孵化后无法获取食物会阻止这两个参数发生变化。结合雏鸡胚胎/新生期过渡期间肝脏脂肪生成酶活性的变化以及胰岛素在协调发育过程中的作用对这些结果进行了讨论。
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