Kumar Naveen, Surendran Deepanjali, Bammigatti Chanaveerappa
Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
BMJ Case Rep. 2018 Mar 28;2018:bcr-2018-224222. doi: 10.1136/bcr-2018-224222.
A young female in her early 20s presented with low-grade fever for 1 month, puffiness of face and abdominal distension for 15 days. Evaluation revealed pancytopenia with normocellular marrow, hypocomplementaemia and Coomb's positive haemolytic anaemia. She had angioedema with laryngospasm and worsening facial oedema which had dramatic response to steroids. Further workup lead to a diagnosis of systemic lupus erythematosus with neuropsychiatric involvement. Treatment with pulse steroids and cyclophosphamide resulted in dramatic improvement of her symptoms with no recurrence of angioedema during her follow-up visits.
一名20岁出头的年轻女性出现低热1个月，面部肿胀和腹胀15天。检查发现全血细胞减少伴正常细胞骨髓、低补体血症和库姆斯试验阳性的溶血性贫血。她有血管性水肿伴喉痉挛，面部水肿加重，对类固醇有显著反应。进一步检查诊断为系统性红斑狼疮伴神经精神系统受累。脉冲类固醇和环磷酰胺治疗使她的症状显著改善，随访期间血管性水肿未复发。
