Sakai Yohei
Food Ingredients & Technology Institute, R&D Division, Morinaga Milk Industry Co., Ltd., Zama, Japan.
Clin Calcium. 2018;28(4):513-517.
Lactulose is a non-digestible oligosaccharide, consisting of galactose and fructose. Bifidobacteria in the large intestine assimilate and metabolize lactulose, which has not been degraded or absorbed by humans, and they subsequently proliferate. Predominant bifidobacteria release short chain fatty acids, such as acetic acid and lactic acid, into the intestinal tract by lactulose metabolization, which lowers the intraluminal pH. As a result, the calcium that has flowed into the large intestine without absorption in the small intestine is solubilized and absorbed in the large intestine. So that means continuous ingestion of lactulose might contribute to bone health by increasing the absorption efficiency of calcium.
乳果糖是一种不可消化的低聚糖，由半乳糖和果糖组成。大肠中的双歧杆菌会吸收并代谢未被人体降解或吸收的乳果糖，随后双歧杆菌大量繁殖。占主导地位的双歧杆菌通过乳果糖代谢向肠道释放短链脂肪酸，如乙酸和乳酸，这会降低肠腔内的pH值。结果，在小肠中未被吸收而流入大肠的钙被溶解并在大肠中被吸收。这意味着持续摄入乳果糖可能通过提高钙的吸收效率而有助于骨骼健康。
