[Milk, Daily products and Bone health.The effect of lactulose on bone health.].

Lactulose is a non-digestible oligosaccharide, consisting of galactose and fructose. Bifidobacteria in the large intestine assimilate and metabolize lactulose, which has not been degraded or absorbed by humans, and they subsequently proliferate. Predominant bifidobacteria release short chain fatty acids, such as acetic acid and lactic acid, into the intestinal tract by lactulose metabolization, which lowers the intraluminal pH. As a result, the calcium that has flowed into the large intestine without absorption in the small intestine is solubilized and absorbed in the large intestine. So that means continuous ingestion of lactulose might contribute to bone health by increasing the absorption efficiency of calcium.