Vaid Rajesh Kumar, Shanmugasundaram Karuppusamy, Anand Taruna, Bera Bidhan Chandra, Tigga Mamta, Dedar Ramesh, Riyesh Thachamvally, Bardwaj Shashank, Virmani Nitin, Tripathi Bhupendra Nath, Singh Rajkumar
Bacteriology Laboratory, National Centre for Veterinary Type Cultures, National Research Centre on Equines, 125 001 Haryana, India.
J Equine Sci. 2018;29(1):25-31. doi: 10.1294/jes.29.25. Epub 2018 Mar 23.
is a well-known Gram-negative bacterial pathogen causing a plethora of diseases in different animals. Although its infection has been reported from pigs and dogs in India, no report of B. bronchiseptica from horses is described. We report for the first time, isolation, identification and characterization of strains of B. bronchiseptica from respiratory infection in horses from different states in India. The antimicrobial susceptibility testing showed resistance to penicillins, ceftazidime, and chloramphanicol. The virulence capability of the strains was confirmed by sequencing genes such as adenylate cyclase toxin (cyaA), bordetella virulence gene (bvgA) and by PCR detection of flagellin gene (fla). We demonstrate the involvement of B. bronchiseptica strains in respiratory tract infection in horses in India.
是一种著名的革兰氏阴性细菌病原体，可在不同动物中引发多种疾病。尽管在印度已报道猪和狗感染该病菌，但尚无马感染支气管败血波氏杆菌的报告。我们首次报告了从印度不同邦的马呼吸道感染中分离、鉴定和表征支气管败血波氏杆菌菌株的情况。抗菌药敏试验显示这些菌株对青霉素、头孢他啶和氯霉素耐药。通过对腺苷酸环化酶毒素（cyaA）、博德特氏菌毒力基因（bvgA）等基因进行测序以及通过PCR检测鞭毛蛋白基因（fla），证实了这些菌株的毒力。我们证明了支气管败血波氏杆菌菌株在印度马呼吸道感染中的作用。
