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青少年的巨大腮腺脂肪母细胞瘤

Large Parotid Gland Lipoblastoma in a Teenager.

作者信息

Jandali Danny, Heilingoetter Ashley, Ghai Ritu, Jeffe Jill, Al-Khudari Samer

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, Rush University Medical Center, Chicago, IL, United States.

Rush Medical College, Rush University Medical Center, Chicago, IL, United States.

出版信息

Front Pediatr. 2018 Mar 9;6:50. doi: 10.3389/fped.2018.00050. eCollection 2018.

Abstract

BACKGROUND

Lipoblastomas are rare benign neoplasms that arise from fetal white fat cells. They are typically found in children under the age of 3 and have been reported in the mediastinum, extremities, and infrequently in the head and neck. We present a rare case of a lipoblastoma arising from the parotid gland and the first known report of a parotid lipoblastoma in a teenager.

CASE PRESENTATION

A 15-year-old male presented with a painless, slowly enlarging parotid mass and left facial swelling. A fine needle aspiration was non-diagnostic and initial MRI showed a 3.8 cm × 5.0 cm × 4.0 cm fatty lesion involving the superficial and deep lobes of the left parotid gland and masticator space with widening of the stylo-mandibular tunnel and thinning of the adjacent mandibular condyle. The patient was taken to the operating room, and the mass was excised under general anesthesia a transcervical parotid approach with facial nerve monitoring. The most superficial aspect of the parotid bed was spared and with upper and lower divisions of the facial nerve preserved. The tumor, which primarily involved the deep lobe of the parotid, was entirely excised. Final pathology revealed a 5.2 cm lipoblastoma. The patient did well post-operatively with full function of the facial nerve and 20 months of follow up without evidence of recurrence.

CONCLUSION

This is the first reported case of a lipoblastoma of the parotid gland in a teenager. Although a rare tumor, it should be considered in the differential diagnosis of a parotid mass in this population.

摘要

背景

脂肪母细胞瘤是一种罕见的良性肿瘤,起源于胎儿白色脂肪细胞。它们通常见于3岁以下儿童,曾报道发生于纵隔、四肢,头颈部较少见。我们报告一例罕见的起源于腮腺的脂肪母细胞瘤,这是已知首例青少年腮腺脂肪母细胞瘤的报道。

病例介绍

一名15岁男性患者,出现无痛性、逐渐增大的腮腺肿块及左侧面部肿胀。细针穿刺活检未能明确诊断,最初的MRI显示一个3.8 cm×5.0 cm×4.0 cm的脂肪性病变,累及左侧腮腺浅叶和深叶以及咀嚼肌间隙,茎突下颌管增宽,相邻下颌髁变薄。患者被送往手术室,在全身麻醉下采用经颈腮腺入路并进行面神经监测切除肿块。腮腺床最表浅部分得以保留,面神经上下支得以保留。主要累及腮腺深叶的肿瘤被完整切除。最终病理显示为一个5.2 cm的脂肪母细胞瘤。患者术后恢复良好,面神经功能正常,随访20个月无复发迹象。

结论

这是首例报道的青少年腮腺脂肪母细胞瘤病例。尽管是罕见肿瘤,但在该人群腮腺肿块的鉴别诊断中应予以考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc2/5854657/ab91d493379e/fped-06-00050-g001.jpg

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