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超声引导下微创经皮肾镜取石术治疗6岁以下儿童患者:单中心10年经验

Ultrasound-guided minimally invasive percutaneous nephrolithotomy in the treatment of pediatric patients <6 years: A single-center 10 years' experience.

作者信息

Hong Yang, Xu Qingquan, Huang Xiaobo, Zhu Zhenjie, Yang Qingya, An Lizhe

机构信息

Department of Urology, Peking University People's Hospital, XiCheng District, Beijing, China.

出版信息

Medicine (Baltimore). 2018 Mar;97(13):e0174. doi: 10.1097/MD.0000000000010174.

Abstract

Owing to the fragile kidney and relative small collecting system of pediatric patients, urologists were always reluctant to treat pediatric urolithiasis with PCNL. Here we conduct a study to assess the effectiveness and safety of pediatric patients with renal calculi <6 years.A total of 88 pediatric patients (99 kidney units) <6 years underwent the ultrasound (US)-guided minimally invasive percutaneous nephrolithotomy in our institute from March 2006 to April 2016. The mean age was 30.9 months (range, 7-72 months). The mean stone size was 19.5 mm (range, 10-50 mm). The group included single stone in 35 kidney units, upper ureteral stone in 12 kidney units, multiple stone in 43 kidney units, and staghorn stone in 9 kidney units. The procedure of puncture and dilation were guided by US solely.The mean operation time was 52.3 minutes (range, 15-140 minutes). The mean postoperative length of stay was 6.0 days (3-16 days). Besides, the initial stone free rate (SFR) was 90.9% (90/99) and the final SFR was 96.0% (95/99). The mean hemoglobin drop was 10.9 g/L (range, 1-25 g/L). Postoperative complications occurred in 12 patients including fever in 11 cases and active pleural effusion in 1 case.The US-guided MPCNL is an effective and safety procedure to treat pediatric patients with stone <6 years.

摘要

由于儿科患者的肾脏脆弱且集合系统相对较小,泌尿外科医生一直不愿用经皮肾镜取石术(PCNL)治疗小儿尿路结石。在此,我们进行了一项研究,以评估6岁以下小儿肾结石患者的有效性和安全性。2006年3月至2016年4月,我院共88例6岁以下小儿患者(99个肾单位)接受了超声(US)引导下的微创经皮肾镜取石术。平均年龄为30.9个月(范围7 - 72个月)。平均结石大小为19.5毫米(范围10 - 50毫米)。该组包括35个肾单位为单发结石病例,12个肾单位为输尿管上段结石病例,43个肾单位为多发结石病例,9个肾单位为鹿角形结石病例。穿刺和扩张过程仅由超声引导。平均手术时间为52.3分钟(范围15 - 140分钟)。术后平均住院时间为6.0天(3 - 16天)。此外,初始结石清除率(SFR)为90.9%(90/99),最终结石清除率为96.0%(95/99)。平均血红蛋白下降10.9克/升(范围1 - 25克/升)。12例患者出现术后并发症,包括11例发热和1例活动性胸腔积液。超声引导下的MPCNL是治疗6岁以下小儿结石患者的一种有效且安全的手术方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfa0/5895361/135fc1f34ea0/medi-97-e0174-g002.jpg

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