Ozden Ender, Sahin Ahmet, Tan Bekir, Doğan Hasan Serkan, Eren Murat Tugrul, Tekgül Serdar
Department of Urology, Hacettepe University, Ankara, Turkey.
J Pediatr Urol. 2008 Aug;4(4):295-8. doi: 10.1016/j.jpurol.2008.01.212. Epub 2008 Mar 20.
We report our experience with percutaneous nephrolithotomy (PNL) therapy for staghorn or complex pediatric renal calculi.
We retrospectively analyzed the case records of 105 patients younger than 17 years who underwent PNL. The cases included 53 complex calculi analyzed in 51 patients. We defined complex calculi as either staghorn or those with a stone bulk larger than 300 mm(2), involving more than one calix, the upper ureter or stone in anomalous kidney.
Mean age of patients with complex calculi was 9.7+/-0.7 years and stone burden was 654+/-92.4mm(2). The median duration of PNL was 90+/-4.7 (30-220) min. Complete clearance was achieved in 39 patients (73.6%). Of these, 32 (60.4%) required a single tract, while 21 (39.6%) required multiple tracts. With subsequent shock wave lithotripsy and PNL, the clearance rate increased to 86.8%. The average hemoglobin drop was 1.6+/-0.16 g/dL. Assessing the factors affecting the hemoglobin drop, the number of tracts (P=0.01) and size of tracts (P=0.002) were found to be significant. The mean change in serum creatinine concentration between preoperative and postoperative measurements was -0.01+/-0.02 mg/dL, for both patients with a single tract and those with multiple tracts.
PNL is safe and effective in the management of staghorn and complex renal calculi in children. Tract dilatation and number of tracts are important factors in reducing blood loss.
我们报告经皮肾镜取石术(PNL)治疗鹿角形或复杂性小儿肾结石的经验。
我们回顾性分析了105例17岁以下接受PNL治疗患者的病例记录。其中包括51例患者的53例复杂性结石。我们将复杂性结石定义为鹿角形结石或结石体积大于300 mm²、累及多个肾盏、上段输尿管或异位肾内结石。
复杂性结石患者的平均年龄为9.7±0.7岁,结石负荷为654±92.4 mm²。PNL的中位持续时间为90±4.7(30 - 220)分钟。39例患者(73.6%)结石完全清除。其中,32例(60.4%)需要单通道,21例(39.6%)需要多通道。经过后续的冲击波碎石术和PNL,结石清除率提高到86.8%。血红蛋白平均下降1.6±0.16 g/dL。评估影响血红蛋白下降的因素,发现通道数量(P = 0.01)和通道大小(P = 0.002)具有显著性。单通道和多通道患者术前和术后血清肌酐浓度的平均变化均为 -0.01±0.02 mg/dL。
PNL治疗小儿鹿角形和复杂性肾结石安全有效。通道扩张和通道数量是减少失血的重要因素。