Xu Feng, Shao Ziyang, Yang Gongxing, Gu Aichun, Jiang Mengda, Pan Yifan, Ma Yubo
Department of Nuclear Medicine Department of Oral & Maxillofacial - Head & Neck Oncology Department of Radiology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
Medicine (Baltimore). 2018 Mar;97(13):e0239. doi: 10.1097/MD.0000000000010239.
Because of its rarity, the exact imaging features of ectopic thyroid are poorly known.To analyze the value of scintigraphy, computed tomography (CT), magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT)/CT in the diagnosis of ectopic thyroid in the head and neck.First, we retrospectively analyzed the scintigraphy, CT, MRI, and SPECT/CT images from 25 masses (22 patients) suspected of head and neck ectopic thyroid from 2006 to 2017 at the Shanghai Ninth People's Hospital. Each mass was imaged by nuclear imaging (scintigraphy with or without SPECT/CT) and radiological exam (CT and/or MRI). Pathological examination was considered as the gold standard. Secondly, thirteen malignant ectopic thyroids in the head and neck reported in the English literature from 2001 to 2017 were retrieved for comparison.The accuracy of scintigraphy was not significantly higher than that of CT (94.7%, vs 89.5%, P > .99) or MRI (92.3%, vs 84.6%, P > .99). Five masses which underwent scintigraphy with SPECT/CT were all true positive, while 1 was false negative on MRI, and 2 were false negative on CT. Compared to the benign ectopic thyroids in our study, the 13 malignant ectopic thyroids retrieved from the literature were grossly the same in shape, margins, and invasion on CT or MRI.The number of patients was limited, but scintigraphy combined with SPECT/CT could be a reliable method for the diagnosis of ectopic thyroid. Benign and malignant ectopic thyroids appear to be similar in shapes, margins, and invasion on CT or MRI.
由于其罕见性，异位甲状腺的确切影像学特征鲜为人知。分析闪烁扫描、计算机断层扫描（CT）、磁共振成像（MRI）和单光子发射计算机断层扫描（SPECT）/CT在诊断头颈部异位甲状腺中的价值。首先，我们回顾性分析了2006年至2017年上海第九人民医院25个肿物（22例患者）疑似头颈部异位甲状腺的闪烁扫描、CT、MRI和SPECT/CT图像。每个肿物均通过核成像（闪烁扫描联合或不联合SPECT/CT）和放射学检查（CT和/或MRI）成像。病理检查被视为金标准。其次，检索2001年至2017年英文文献中报道的13例头颈部恶性异位甲状腺进行比较。闪烁扫描的准确性并不显著高于CT（94.7%对89.5%，P＞0.99）或MRI（92.3%对84.6%，P＞0.99）。5例行SPECT/CT闪烁扫描的肿物均为真阳性，而MRI有1例假阴性，CT有2例假阴性。与我们研究中的良性异位甲状腺相比，从文献中检索出的13例恶性异位甲状腺在CT或MRI上的形态、边缘和侵犯情况大致相同。患者数量有限，但闪烁扫描联合SPECT/CT可能是诊断异位甲状腺的可靠方法。良性和恶性异位甲状腺在CT或MRI上的形态、边缘和侵犯情况似乎相似。
