Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.
Retin Cases Brief Rep. 2020 Fall;14(4):310-314. doi: 10.1097/ICB.0000000000000738.
To report a case of acute macular neuroretinopathy in a patient with Susac syndrome.
Case report.
A 39-year-old male patient presented with severe headache, photopsias, and a sudden onset of hearing loss in the right ear. Fluorescein angiography of the right eye revealed multiple branch retinal artery occlusions. Clinical presentation of encephalopathy, hearing loss, and branch retinal artery occlusions, along with characteristic magnetic resonance imaging findings, led to a diagnosis of Susac syndrome. Despite aggressive immunosuppression for four months, the patient later presented with acute macular neuroretinopathy in the left eye.
Acute macular neuroretinopathy and Susac is a new association of two well-defined disorders. The concurrence of both disorders supports retinal ischemia as the proximate cause of acute macular neuroretinopathy and inflammation as a potential etiology.
报告一例伴有 Susac 综合征的急性黄斑神经视网膜病变患者。
病例报告。
一名 39 岁男性患者以剧烈头痛、闪光和右侧突发性听力丧失为首发症状。右眼荧光素血管造影显示多发性分支视网膜动脉阻塞。脑病、听力损失和分支视网膜动脉阻塞的临床表现，加上特征性磁共振成像发现，导致 Susac 综合征的诊断。尽管进行了为期四个月的强化免疫抑制治疗，但该患者后来左眼出现急性黄斑神经视网膜病变。
急性黄斑神经视网膜病变和 Susac 是两种明确疾病的新关联。两种疾病的同时存在支持视网膜缺血是急性黄斑神经视网膜病变的直接原因，炎症是潜在病因。
