Entezari Morteza, Karimi Saeed, Feizi Mohammadali
Department of Ophthalmology, Ophthalmic Research Center, Torfeh Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Radiology, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Indian J Ophthalmol. 2016 Sep;64(9):678-680. doi: 10.4103/0301-4738.194334.
Susac syndrome (SS) is a rare retinal-cochlear-cerebral disease with an unclear etiology. A 35-year-old man presented with sudden painless vision loss in the right eye and 2 months later in the left eye with hemiparesis, behavioral changes, and hearing loss. Ophthalmic examinations revealed multiple branch retinal artery occlusions (BRAOs) in both eyes. Brain magnetic resonance imaging showed inflammatory changes with multiple "punched-out" lesions in the corpus callosum which confirmed the diagnosis of SS. Despite intravenous and oral corticosteroid therapy, the disease progressed with the development of new BRAOs, low vision in both eyes, and disability. Prompt diagnosis and early treatment may save the vision and even patient's life.
Susac综合征（SS）是一种病因不明的罕见视网膜-耳蜗-脑疾病。一名35岁男性出现右眼突然无痛性视力丧失，2个月后左眼出现视力丧失，并伴有偏瘫、行为改变和听力丧失。眼科检查发现双眼多发视网膜分支动脉阻塞（BRAO）。脑部磁共振成像显示胼胝体有多处“穿凿样”病变的炎症改变，确诊为SS。尽管进行了静脉和口服皮质类固醇治疗，但疾病仍进展，出现新的BRAO、双眼视力低下和残疾。及时诊断和早期治疗可能挽救视力甚至患者生命。
