Currie Geoffrey M
Faculty of Science, Charles Sturt University, Wagga Wagga, New South Wales, Australia, and Regis University, Boston, Massachusetts
J Nucl Med Technol. 2018 Jun;46(2):81-86. doi: 10.2967/jnmt.117.199588. Epub 2018 Mar 29.
There is an emerging need for greater understanding of pharmacology principles among technical staff. Indeed, the responsibility of dose preparation and administration, under any level of supervision, demands a foundational understanding of pharmacology. This is true for radiopharmaceuticals, contrast media, and pharmaceutical interventions or adjunctive medications. Regulation around the same might suggest a need to embed pharmacology theory in undergraduate education programs, and there is a need to disseminate that same foundational understanding to practicing clinicians. Moreover, pharmacology foundations can provide a key understanding of the principles that underpin quantitative techniques (e.g., pharmacokinetics). This article is the first in a series that aims to enhance the understanding of pharmacologic principles relevant to nuclear medicine. This article will deal with the introductory concepts, terminology, and principles that underpin the concepts to be discussed in the remainder of the series. The second article will build on the pharmacodynamic principles examined in this article with a treatment of pharmacokinetics. Article 3 will outline pharmacology relevant to pharmaceutical interventions and adjunctive medications used in general nuclear medicine, article 4 will cover pharmacology relevant to pharmaceutical interventions and adjunctive medications used in nuclear cardiology, and article 5 will discuss the pharmacology related to contrast media associated with CT and MRI. The final article (6) in the series will examine the pharmacology of drugs associated with the crash cart/emergency trolley.
技术人员对药理学原理的深入理解需求日益凸显。事实上，无论在何种监督级别下，剂量准备和给药的职责都需要对药理学有基本的理解。对于放射性药物、造影剂以及药物干预或辅助药物而言都是如此。围绕此方面的监管可能意味着有必要将药理学理论纳入本科教育课程，并且有必要向执业临床医生传播同样的基本理解。此外，药理学基础能够提供对支撑定量技术（如药代动力学）原理的关键理解。本文是旨在增进对与核医学相关药理学原理理解的系列文章中的第一篇。本文将探讨该系列其余部分所讨论概念的入门概念、术语和原理。第二篇文章将在本文所探讨的药效学原理基础上进一步探讨药代动力学。第3篇文章将概述与一般核医学中使用的药物干预和辅助药物相关的药理学，第4篇文章将涵盖与核心脏病学中使用的药物干预和辅助药物相关的药理学，第5篇文章将讨论与CT和MRI相关的造影剂的药理学。该系列的最后一篇文章（第6篇）将研究与急救推车/急诊推车上药物相关的药理学。
