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毒液免疫疗法与妊娠

Venom immunotherapy and pregnancy.

作者信息

Pałgan Krzysztof, Żbikowska-Götz Magdalena, Chrzaniecka Elżbieta, Bartuzi Zbigniew

机构信息

Department of Allergology, Clinical Immunology and Internal Diseases, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.

出版信息

Postepy Dermatol Alergol. 2018 Feb;35(1):90-92. doi: 10.5114/ada.2018.73168. Epub 2018 Feb 20.

Abstract

INTRODUCTIONS

The efficiency of venom immunotherapy (VIT) has been well documented by many studies. However, the most important for VIT is safety, particularly for a pregnant woman and a fetus.

AIM

To establish the influence of continuation of VIT on pregnant women and offspring.

MATERIAL AND METHODS

The 6 women became pregnant during a specific immunotherapy. We retrospectively analyzed the influence of the immunotherapy on any complications for the pregnant women and their infants.

RESULTS

Of the 6 patients who participated in this study, four had hyperemesis gravidarum, nausea, and heartburn, and two of them had gestational diabetes mellitus symptoms, typical of pregnancy. The observation indicated that VIT was safe for the pregnant women and their offspring.

CONCLUSIONS

The VIT is an appropriate therapeutic method for most patients with severe anaphylactic reactions after a hymenoptera sting. The observation indicated that VIT is safe for pregnant women and for their infants.

摘要

引言

许多研究已充分证明了毒液免疫疗法(VIT)的有效性。然而,对于VIT而言,最重要的是安全性,尤其是对孕妇和胎儿。

目的

确定继续进行VIT对孕妇及其后代的影响。

材料与方法

6名女性在特定免疫治疗期间怀孕。我们回顾性分析了免疫治疗对孕妇及其婴儿的任何并发症的影响。

结果

参与本研究的6名患者中,4名有妊娠剧吐、恶心和烧心症状,其中2名有典型的妊娠糖尿病症状。观察表明,VIT对孕妇及其后代是安全的。

结论

VIT是大多数膜翅目昆虫叮咬后发生严重过敏反应患者的合适治疗方法。观察表明,VIT对孕妇及其婴儿是安全的。

相似文献

1
Venom immunotherapy and pregnancy.毒液免疫疗法与妊娠
Postepy Dermatol Alergol. 2018 Feb;35(1):90-92. doi: 10.5114/ada.2018.73168. Epub 2018 Feb 20.
3
Venom immunotherapy in the Hymenoptera-allergic pregnant patient.膜翅目过敏孕妇的毒液免疫疗法
J Allergy Clin Immunol. 1990 Apr;85(4):709-12. doi: 10.1016/0091-6749(90)90188-a.

本文引用的文献

3
Management and Prevention of Anaphylaxis.过敏反应的管理与预防
F1000Res. 2015 Dec 22;4. doi: 10.12688/f1000research.7181.1. eCollection 2015.
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Anaphylaxis in children and adolescents: The European Anaphylaxis Registry.儿童和青少年过敏反应:欧洲过敏反应登记处。
J Allergy Clin Immunol. 2016 Apr;137(4):1128-1137.e1. doi: 10.1016/j.jaci.2015.11.015. Epub 2016 Jan 21.
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Allergen immunotherapy in pregnancy.孕期变应原免疫疗法。
Allergy Asthma Clin Immunol. 2015 Nov 10;11:31. doi: 10.1186/s13223-015-0096-7. eCollection 2015.
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Sex-related clinical aspects in insect venom anaphylaxis.昆虫毒液过敏反应中的性别相关临床特征。
Int J Immunopathol Pharmacol. 2015 Jun;28(2):187-93. doi: 10.1177/0394632015586143. Epub 2015 Jun 15.
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Clinical immunology review series: an approach to desensitization.临床免疫学综述系列:脱敏方法。
Clin Exp Immunol. 2011 Feb;163(2):131-46. doi: 10.1111/j.1365-2249.2010.04296.x. Epub 2010 Dec 22.
10
Venom immunotherapy in the Hymenoptera-allergic pregnant patient.膜翅目过敏孕妇的毒液免疫疗法
J Allergy Clin Immunol. 1990 Apr;85(4):709-12. doi: 10.1016/0091-6749(90)90188-a.

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