Gourgon R, Cohen Solal A, Himbert D, Aumont M C
Service de Cardiologie, Hôpital Bichat, Paris.
Rev Mal Respir. 1987;4(4):151-8.
Left ventricular failure is defined as an inability to maintain, under resting conditions, a cardiac output sufficient for the oxygen requirement. It is accompanied by a rise in trans-mural ventricular filling pressure and/or a reduction in systolic volume. It may be linked to an alteration in the systolic performance and/or an alteration in the characteristics of the left ventricle. The compensatory mechanisms are represented by the noradrenergic stimulation; a rise in the muscular mass of the left ventricle and the associated changes in its geometry the heterometric regulation of Frank Starling. Some peripheral adaptive mechanisms such as salt and water retention, arteriolar vaso-constriction and a rise in the peripheral extraction of oxygen contribute to compensating for the lower systemic cardiac output.
左心室衰竭的定义为在静息状态下无法维持足以满足氧需求的心输出量。它伴随着跨壁心室充盈压升高和/或收缩期容积降低。它可能与收缩功能改变和/或左心室特性改变有关。代偿机制表现为去甲肾上腺素能刺激；左心室肌肉质量增加及其几何形状的相关变化，即弗兰克 - 斯塔林定律的异长调节。一些外周适应性机制，如盐和水潴留、小动脉血管收缩以及外周氧摄取增加，有助于代偿较低的心输出量。
