Wang Peng-Fei, Deng Shi-Dong, Qu Jing, Yu Shi-Shan
State Key Laboratory of Bioactive Substance and Function of Natural Medicines， Institute of Materia Medica， Chinese Academy of Medical Sciences and Peking Union Medical College， Beijing 100050， China.
Zhongguo Zhong Yao Za Zhi. 2018 Feb;43(3):532-536. doi: 10.19540/j.cnki.cjcmm.20180104.006.
Through the methods of polyamide resin， Sephadex LH-20， ODS column chromatography and preparative HPLC etc.， 7 compounds were isolated from the 70% ethanol extract of the fruits of Xanthium chinense. Based on ESI-MS and NMR data， the structures of these compounds were identified as pungiolide O(1)， grasshopper ketone(2)， icariside F₂(3)， 7-[(β-D-apiofuranosyl-(1→6)-β-D-glucopyranosyl)oxymethy]-8，8-dimethyl-4，8-dihydrobenzo[1，4]thiazine-3，5-dione(4)，(6R，9S)-3-oxo-α-ionol β-D-glucopyranoside(5)， cryptochlorogenic acid methyl ester(6)， and chlorogenic acid methyl ester(7). Among them， compound 1 is a new compound.
通过聚酰胺树脂、葡聚糖凝胶LH - 20、ODS柱色谱和制备型高效液相色谱等方法，从苍耳果实70%乙醇提取物中分离得到7个化合物。基于电喷雾电离质谱（ESI - MS）和核磁共振（NMR）数据，鉴定这些化合物的结构分别为苍耳内酯O(1)、蚱蜢酮(2)、淫羊藿苷F₂(3)、7 - [(β - D - 阿吡喃糖基 - (1→6) - β - D - 吡喃葡萄糖基)氧甲基] - 8,8 - 二甲基 - 4,8 - 二氢苯并[1,4]噻嗪 - 3,5 - 二酮(4)、(6R,9S) - 3 - 氧代 - α - 紫罗兰醇β - D - 葡萄糖苷(5)、隐绿原酸甲酯(6)和绿原酸甲酯(7)。其中，化合物1为新化合物。
