Centre for Trials Research, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.
Centre for the Development and Evaluation of Complex Interventions for Public Health Improvement (DECIPHer), College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.
J Epidemiol Community Health. 2018 Aug;72(8):711-714. doi: 10.1136/jech-2017-210363. Epub 2018 Mar 30.
To examine the combined influence of changes in physical activity, diet, smoking and alcohol consumption on all-cause mortality.
Health behaviours were assessed in 1984/1985 and 1991/1992 in 8123 adults from the UK (4666 women, median age 41.0 years). An unhealthy lifestyle score was calculated, allocating one point for smoking, fruits and vegetables <3 times a day, physical activity <2 hours a week and >14 units (women) or >21 units of alcohol (men) per week.
There were 2003 deaths over a median follow-up of 6.6 years (IQR 5.9-7.2) following the resurvey. The modal change in the unhealthy lifestyle score was zero, 41.8% had the same score, 35.5% decreased and 22.7% increased score between surveys. A one unit decrease in the unhealthy lifestyle score was not associated with a beneficial effect on mortality (HR 0.93; 95% CI 0.83 to 1.04). A one unit increase in the unhealthy lifestyle score increased the risk of mortality (adjusted HR 1.09; 95% CI 1.01 to 1.18).
In this general population sample, the adoption of an unhealthy lifestyle was associated with an increased risk of mortality.
研究身体活动、饮食、吸烟和饮酒习惯变化对全因死亡率的综合影响。
在英国，对 8123 名成年人（4666 名女性，中位年龄 41.0 岁）进行了健康行为评估，评估时间分别为 1984/1985 年和 1991/1992 年。根据吸烟、每天水果和蔬菜摄入量<3 次、每周身体活动量<2 小时和每周摄入>14 单位（女性）或>21 单位（男性）酒精计算出不健康生活方式评分，每一项得 1 分。
中位随访 6.6 年（IQR 5.9-7.2）后，有 2003 人死亡。不健康生活方式评分的模态变化为 0 分，41.8%的人评分相同，35.5%的人评分下降，22.7%的人评分增加。不健康生活方式评分每降低 1 分，与死亡率降低无关（HR 0.93；95%CI 0.83-1.04）。不健康生活方式评分每增加 1 分，死亡率风险增加（调整 HR 1.09；95%CI 1.01-1.18）。
在这个普通人群样本中，采用不健康的生活方式与死亡率增加相关。
