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本文引用的文献

1
Risk of preterm birth following surgical treatment for cervical disease: executive summary of a recent symposium.宫颈疾病手术治疗后早产的风险:近期研讨会执行摘要
BJOG. 2016 Aug;123(9):1426-9. doi: 10.1111/1471-0528.13839. Epub 2015 Dec 23.
2
Length but not transverse diameter of the excision specimen for high-grade cervical intraepithelial neoplasia (CIN 2-3) is a predictor of pregnancy outcome.高级别宫颈上皮内瘤变(CIN 2-3)切除标本的长度而非横径是妊娠结局的一个预测指标。
Eur J Cancer Prev. 2016 Sep;25(5):416-22. doi: 10.1097/CEJ.0000000000000196.
3
Trends in the incidence of cervical cancer and severe precancerous lesions in Denmark, 1997-2012.1997 - 2012年丹麦宫颈癌及严重癌前病变的发病率趋势
Cancer Causes Control. 2015 Aug;26(8):1105-16. doi: 10.1007/s10552-015-0603-7. Epub 2015 Jun 2.
4
Risk of preterm delivery with increasing depth of excision for cervical intraepithelial neoplasia in England: nested case-control study.英国宫颈上皮内瘤变切除深度增加与早产风险:巢式病例对照研究
BMJ. 2014 Nov 5;349:g6223. doi: 10.1136/bmj.g6223.
5
Loop electrosurgical excision procedure: an effective, inexpensive, and durable teaching model.环形电外科切除术:一种有效、廉价且持久的教学模式。
Am J Obstet Gynecol. 2014 Dec;211(6):706.e1-3. doi: 10.1016/j.ajog.2014.05.047. Epub 2014 Jun 2.
6
Systematic review of skills transfer after surgical simulation-based training.基于手术模拟训练的技能转移的系统评价。
Br J Surg. 2014 Aug;101(9):1063-76. doi: 10.1002/bjs.9482. Epub 2014 May 15.
7
Surgery for cervical intraepithelial neoplasia.宫颈上皮内瘤变的手术治疗
Cochrane Database Syst Rev. 2013 Dec 4;2013(12):CD001318. doi: 10.1002/14651858.CD001318.pub3.
8
Validation of a structured training and assessment curriculum for technical skill acquisition in minimally invasive surgery: a randomized controlled trial.经结构训练和评估课程验证,微创外科技术技能习得:一项随机对照试验。
Ann Surg. 2013 Feb;257(2):224-30. doi: 10.1097/SLA.0b013e31827051cd.
9
Conization of the uterine cervix: does the level of gynecologist's training predict margin status?子宫颈锥切术:妇科医生的培训水平是否可预测切缘状态?
Int J Gynecol Pathol. 2012 Jul;31(4):382-6. doi: 10.1097/PGP.0b013e318242118c.
10
A novel training model for the loop electrosurgical excision procedure: an innovative replica helped workshop participants improve their LEEP.一种新的环行电切术培训模型:创新复制品帮助工作坊参与者提高 LEEP 水平。
Am J Obstet Gynecol. 2012 Jun;206(6):535.e1-4. doi: 10.1016/j.ajog.2012.01.016. Epub 2012 Jan 13.

训练水平对宫颈锥切术时宫颈锥大小及切缘状态的影响:一项回顾性研究

Influence of training level on cervical cone size and resection margin status at conization: a retrospective study.

作者信息

Montanari Eliana, Grimm Christoph, Schwameis Richard, Kuessel Lorenz, Polterauer Stephan, Paternostro Chiara, Husslein Heinrich

机构信息

Department of Gynecology and Obstetrics, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

出版信息

Arch Gynecol Obstet. 2018 Jun;297(6):1517-1523. doi: 10.1007/s00404-018-4761-1. Epub 2018 Mar 30.

DOI:10.1007/s00404-018-4761-1
PMID:29602979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5945722/
Abstract

OBJECTIVE

To explore whether a surgeon's training level influences the rate of incomplete resections or the amount of resected cervical tissue in women treated with large loop excision of the transformation zone (LLETZ).

METHODS

The present study is a retrospective analysis of the data of women who had undergone LLETZ for cervical intraepithelial neoplasia (CIN) within the years 2004-2008 at the Medical University of Vienna. Women were grouped according to the level of training of the operating surgeon (i.e, resident or staff gynecologist) and univariate and multivariable analyses were performed to identify independent risk factors for excessive cone volume, depth and incomplete resection (i.e., positive resection margin).

RESULTS

Data of 912 women were analysed. Residents had a significantly larger cone volume [median 2681 (interquartile range 1472-4109) mm] than staff gynecologists [2094 (1309-3402) mm] (p = 0.001) in univariate analysis. The depth of resection and the rate of incomplete resection were comparable between both groups. In a binary logistic multivariable analysis, the level of training as well as patient's age was significantly associated with a cone volume larger than 2500 mm.

CONCLUSION

Conization performed by residents as opposed to staff gynecologists does not compromise the procedure's effectiveness but may expose women to a potential additional risk for adverse obstetrical outcomes due to excessive resection of cervical tissue.

摘要

目的

探讨在接受转化区大环形切除术(LLETZ)治疗的女性中,外科医生的培训水平是否会影响不完全切除率或宫颈组织切除量。

方法

本研究是对2004年至2008年在维也纳医科大学因宫颈上皮内瘤变(CIN)接受LLETZ治疗的女性数据进行的回顾性分析。根据手术医生的培训水平(即住院医师或妇科主治医师)对女性进行分组,并进行单因素和多因素分析,以确定锥切体积过大、深度和不完全切除(即切缘阳性)的独立危险因素。

结果

分析了912名女性的数据。在单因素分析中,住院医师的锥切体积[中位数2681(四分位间距1472 - 4109)mm]显著大于妇科主治医师[2094(1309 - 3402)mm](p = 0.001)。两组之间的切除深度和不完全切除率相当。在二元逻辑多因素分析中,培训水平以及患者年龄与锥切体积大于2500 mm显著相关。

结论

与妇科主治医师相比,住院医师进行的锥切术不会影响手术效果,但由于宫颈组织切除过多,可能会使女性面临不良产科结局的潜在额外风险。