Montanari Eliana, Grimm Christoph, Schwameis Richard, Kuessel Lorenz, Polterauer Stephan, Paternostro Chiara, Husslein Heinrich
Department of Gynecology and Obstetrics, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Arch Gynecol Obstet. 2018 Jun;297(6):1517-1523. doi: 10.1007/s00404-018-4761-1. Epub 2018 Mar 30.
To explore whether a surgeon's training level influences the rate of incomplete resections or the amount of resected cervical tissue in women treated with large loop excision of the transformation zone (LLETZ).
The present study is a retrospective analysis of the data of women who had undergone LLETZ for cervical intraepithelial neoplasia (CIN) within the years 2004-2008 at the Medical University of Vienna. Women were grouped according to the level of training of the operating surgeon (i.e, resident or staff gynecologist) and univariate and multivariable analyses were performed to identify independent risk factors for excessive cone volume, depth and incomplete resection (i.e., positive resection margin).
Data of 912 women were analysed. Residents had a significantly larger cone volume [median 2681 (interquartile range 1472-4109) mm] than staff gynecologists [2094 (1309-3402) mm] (p = 0.001) in univariate analysis. The depth of resection and the rate of incomplete resection were comparable between both groups. In a binary logistic multivariable analysis, the level of training as well as patient's age was significantly associated with a cone volume larger than 2500 mm.
Conization performed by residents as opposed to staff gynecologists does not compromise the procedure's effectiveness but may expose women to a potential additional risk for adverse obstetrical outcomes due to excessive resection of cervical tissue.
探讨在接受转化区大环形切除术(LLETZ)治疗的女性中,外科医生的培训水平是否会影响不完全切除率或宫颈组织切除量。
本研究是对2004年至2008年在维也纳医科大学因宫颈上皮内瘤变(CIN)接受LLETZ治疗的女性数据进行的回顾性分析。根据手术医生的培训水平(即住院医师或妇科主治医师)对女性进行分组,并进行单因素和多因素分析,以确定锥切体积过大、深度和不完全切除(即切缘阳性)的独立危险因素。
分析了912名女性的数据。在单因素分析中,住院医师的锥切体积[中位数2681(四分位间距1472 - 4109)mm]显著大于妇科主治医师[2094(1309 - 3402)mm](p = 0.001)。两组之间的切除深度和不完全切除率相当。在二元逻辑多因素分析中,培训水平以及患者年龄与锥切体积大于2500 mm显著相关。
与妇科主治医师相比,住院医师进行的锥切术不会影响手术效果,但由于宫颈组织切除过多,可能会使女性面临不良产科结局的潜在额外风险。