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美国兽医内科学会关于细胞毒性化疗药物在兽医临床安全使用的小动物共识声明。

ACVIM small animal consensus statement on safe use of cytotoxic chemotherapeutics in veterinary practice.

作者信息

Smith Annette N, Klahn Shawna, Phillips Brenda, Parshley Lisa, Bennett Peter, Flory Andi, Calderon Rosemary

机构信息

Department of Clinical Sciences, Auburn University College of Veterinary Medicine, Auburn, Alabama.

Department of Small Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, Virginia.

出版信息

J Vet Intern Med. 2018 May;32(3):904-913. doi: 10.1111/jvim.15077. Epub 2018 Mar 30.

Abstract

The purpose of this report is to offer a consensus opinion of ACVIM oncology diplomates and technicians on the safe use of cytotoxic chemotherapeutics in veterinary practice. The focus is on minimizing harm to the personnel exposed to the drugs: veterinary practitioners, veterinary technicians, veterinary staff, and pet owners. The safety of the patient receiving these drugs is also of paramount importance, but is not addressed in this statement. Much of the information presented is based on national recommendations by Occupational Safety and Health Administration, National Institute for Occupational Safety and Health, United States Pharmacopeia, and other published regulations. These directives reflect an abundance of caution to minimize exposure to medical personnel, but large-scale studies about the consequences of long-term occupational exposure are not available in veterinary medicine. Challenges in the delivery of optimal treatment safely and economically to veterinary patients in general practice without access to a veterinary oncologist or other specialist, because of costs or proximity, remain.

摘要

本报告旨在提供美国兽医内科学会肿瘤学专科医师和技术人员对于在兽医实践中安全使用细胞毒性化疗药物的共识性意见。重点在于尽量减少对接触这些药物人员的伤害,这些人员包括兽医从业者、兽医技术人员、兽医工作人员以及宠物主人。接受这些药物治疗的患者的安全也至关重要,但本声明未涉及这方面内容。所呈现的许多信息基于美国职业安全与健康管理局、美国国家职业安全与健康研究所、美国药典以及其他已发布法规的国家建议。这些指令体现了高度的谨慎,以尽量减少医务人员的接触,但兽医医学领域尚无关于长期职业接触后果的大规模研究。由于成本或距离原因,在一般兽医实践中,若无法获得兽医肿瘤学家或其他专科医生的帮助,在安全且经济地为兽医患者提供最佳治疗方面仍存在挑战。

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