Zhai Shaun, Brew Bruce James
Department of Neurology, St. Vincent's Hospital, Sydney, NSW, Australia.
Department of Neurology, St. Vincent's Hospital, Sydney, NSW, Australia; Department of HIV Medicine and Peter Duncan Neurosciences Unit, St. Vincent's Centre for Applied Medical Research, St. Vincent's Hospital, Sydney, NSW, Australia.
Handb Clin Neurol. 2018;152:123-137. doi: 10.1016/B978-0-444-63849-6.00010-4.
Progressive multifocal leukoencephalopathy (PML) is a relatively common complication of HIV disease. In this chapter changes to the epidemiology are discussed along with an update in its pathogenesis and treatment. Immune reconstitution inflammatory syndrome is increasingly frequent in PML; accordingly management strategies and prognosis are detailed.
进行性多灶性白质脑病(PML)是艾滋病的一种相对常见的并发症。本章讨论了其流行病学的变化,以及发病机制和治疗方面的最新进展。免疫重建炎症综合征在PML中越来越常见;因此,详细阐述了管理策略和预后。