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面部和耳垂出现病变之前的广泛瘤型麻风性淋巴结炎:新加坡麻风病的一种不寻常表现

Extensive Lepromatous Lymphadenitis Preceding Lesions on the Face and Earlobes: An Unusual Presentation of Leprosy in Singapore.

作者信息

Yang Shi Yao Sam, Leong Wai Mun Sean, Kasunuran Cruz Maria Teresa, Huang Jing Xiang, Ho Sue-Ann Ju Ee, Aw Chen Wee Derrick, Merchant Reshma A

机构信息

Division of Dermatology, National University Health Systems, Singapore, Singapore.

Division of General Medicine, National University Health Systems, Singapore, Singapore.

出版信息

Case Rep Dermatol. 2018 Feb 14;10(1):35-40. doi: 10.1159/000462959. eCollection 2018 Jan-Apr.

DOI:10.1159/000462959
PMID:29606944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5869576/
Abstract

Leprosy is also known as Hansen disease, as in some countries the diagnosis of leprosy carries a negative stigma and patients fear being shunned as outcasts. Presently, leprosy is primarily limited to specific geographical regions in resource-poor countries. As a result, there is increased difficulty for the younger generation of physicians today to correctly identify leprosy due to a lack of exposure and a low-index of suspicion, particularly in developed countries. In this case, the indurated lesions over the face demonstrated a preference for the outer lateral aspects over the maxillary areas, the nose bridge, and the pinna of the ears consistent with the organism's preference for cooler regions of the body. This was also evident in the other skin lesions affecting the more acral regions of the limbs in the early stage of disease progression. There is a need to keep this infective condition as an alternate diagnosis to all unusual cutaneous lesions.

摘要

麻风病也被称为汉森氏病,因为在一些国家,麻风病的诊断带有负面污名,患者担心会像被遗弃者一样遭到回避。目前,麻风病主要局限于资源匮乏国家的特定地理区域。因此,如今年轻一代的医生由于接触较少且怀疑指数较低,尤其是在发达国家,正确识别麻风病的难度增加。在这种情况下,面部的硬结性病变表现出更倾向于上颌区域、鼻梁和耳廓外侧,这与该病原体偏好身体较凉爽区域一致。在疾病进展早期影响四肢更末端区域的其他皮肤病变中也很明显。有必要将这种感染性疾病作为所有不寻常皮肤病变的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafe/5869576/1b7bb57f7fc7/cde-0010-0035-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafe/5869576/850b53f05034/cde-0010-0035-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafe/5869576/1b7bb57f7fc7/cde-0010-0035-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafe/5869576/850b53f05034/cde-0010-0035-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafe/5869576/1b7bb57f7fc7/cde-0010-0035-g02.jpg

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本文引用的文献

1
The clinical and immunological features of leprosy.麻风病的临床与免疫学特征。
Br Med Bull. 2006;77-78:103-21. doi: 10.1093/bmb/ldl010. Epub 2006 Nov 7.
2
Clinical course of erythema nodosum leprosum: an 11-year cohort study in Hyderabad, India.麻风结节性红斑的临床病程:印度海得拉巴的一项11年队列研究
Am J Trop Med Hyg. 2006 May;74(5):868-79.
3
Leprosy.麻风病
Lancet. 2004 Apr 10;363(9416):1209-19. doi: 10.1016/S0140-6736(04)15952-7.
4
IL-15, an immunomodulator of T cell responses in intracellular infection.白细胞介素-15,一种细胞内感染中T细胞反应的免疫调节剂。
J Immunol. 1997 Jan 15;158(2):800-6.
5
Tumour necrosis factor-alpha (TNF-alpha) synthesis is associated with the skin and peripheral nerve pathology of leprosy reversal reactions.肿瘤坏死因子-α(TNF-α)的合成与麻风反应期的皮肤及周围神经病变相关。
Clin Exp Immunol. 1995 Feb;99(2):196-202. doi: 10.1111/j.1365-2249.1995.tb05532.x.
6
Leprosy: the epidemiology of a slow bacterium.麻风病:一种慢速细菌的流行病学
Epidemiol Rev. 1982;4:161-88. doi: 10.1093/oxfordjournals.epirev.a036245.
7
Attempts to establish the armadillo (Dasypus novemcinctus Linn.) as a model for the study of leprosy. I. Report of lepromatoid leprosy in an experimentally infected armadillo.将犰狳(九带犰狳,Dasypus novemcinctus Linn.)确立为麻风病研究模型的尝试。一、关于一只实验感染犰狳发生瘤型麻风病的报告。
Int J Lepr Other Mycobact Dis. 1971 Jul-Sep;39(3):693-702.