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相似文献

1
Inhibition of suppressor T lymphocytes by murine interferon beta.小鼠β干扰素对抑制性T淋巴细胞的抑制作用
J Exp Med. 1987 Nov 1;166(5):1573-8. doi: 10.1084/jem.166.5.1573.
2
Inhibition of the T suppressor circuit of delayed-type hypersensitivity by interferon.干扰素对迟发型超敏反应中T抑制性回路的抑制作用。
J Immunol. 1984 Nov;133(5):2412-6.
3
Suppressor T cell circuits in contact sensitivity. I. Two mechanistically distinct waves of suppressor T cells occur in mice tolerized with syngeneic DNP-modified lymphoid cells.接触敏感性中的抑制性T细胞回路。I. 在同基因二硝基苯（DNP）修饰的淋巴细胞诱导耐受的小鼠中出现两批机制不同的抑制性T细胞。
J Immunol. 1982 Aug;129(2):461-8.
4
Modulation of suppressor mechanisms in allergic contact dermatitis: 5. Evidence that inhibition of suppressor T lymphocytes by Corynebacterium parvum is mediated by interferon.变应性接触性皮炎中抑制机制的调节：5. 微小棒状杆菌对抑制性T淋巴细胞的抑制作用由干扰素介导的证据
J Invest Dermatol. 1982 Dec;79(6):385-8. doi: 10.1111/1523-1747.ep12530198.
5
Inhibition of suppressor T lymphocytes (Ts) by cimetidine.
J Immunol. 1987 May 1;138(9):2760-3.
6
Differential inhibition of contact sensitivity by suppressor T cells and suppressor factor induced by combined treatment with dinitrobenzenesulphonate and dinitrofluorobenzene.二硝基苯磺酸盐与二硝基氟苯联合处理诱导的抑制性T细胞和抑制因子对接触敏感性的差异抑制作用
Immunology. 1982 Mar;45(3):449-57.
7
Soluble factors in tolerance and contact sensitivity to DNFB in mice. VI. Cellular and lymphokine requirements for stimulating suppressor factor production in vitro.小鼠对二硝基氟苯耐受和接触敏感性中的可溶性因子。VI. 体外刺激抑制因子产生的细胞和淋巴因子需求。
J Immunol. 1986 Oct 1;137(7):2125-31.
8
Selective inhibition of the generation of T suppressor cells of contact sensitivity in vitro by interferon.干扰素在体外对接触敏感性T抑制细胞生成的选择性抑制作用。
J Immunol. 1987 Jun 1;138(11):3684-7.
9
Effect of cyclosporin A on the T-effector and T-suppressor cell response in contact sensitivity.环孢素A对接触性超敏反应中T效应细胞和T抑制细胞反应的影响。
Immunology. 1986 Dec;59(4):503-7.
10
Inhibition of the anti-receptor antibody response of contact sensitivity by interferon.干扰素对接触敏感性抗受体抗体反应的抑制作用。
Immunology. 1985 Jun;55(2):281-7.

引用本文的文献

1
Disruption of murine cardiac allograft acceptance by latent cytomegalovirus.潜伏性巨细胞病毒对小鼠心脏同种异体移植接受的破坏作用。
Am J Transplant. 2009 Jan;9(1):42-53. doi: 10.1111/j.1600-6143.2008.02457.x. Epub 2008 Oct 31.
2
Effect of murine interferon alpha/beta on tumour-induced suppressor function.小鼠α/β干扰素对肿瘤诱导的抑制功能的影响。
Cancer Immunol Immunother. 1994 Dec;39(6):360-6. doi: 10.1007/BF01534422.
3
Interferon-alpha/beta inhibits IgE-dependent histamine release from rat mast cells.干扰素-α/β抑制大鼠肥大细胞中依赖IgE的组胺释放。
Immunology. 1989 Apr;66(4):606-10.
4
Role of beta interferon in resistance to Toxoplasma gondii infection.β干扰素在抗弓形虫感染中的作用。
Infect Immun. 1991 Sep;59(9):3287-90. doi: 10.1128/iai.59.9.3287-3290.1991.
5
An attenuated variant of Coxsackievirus B3 preferentially induces immunoregulatory T cells in vivo.柯萨奇病毒B3的一种减毒变体在体内优先诱导免疫调节性T细胞。
J Virol. 1991 Nov;65(11):5813-9. doi: 10.1128/JVI.65.11.5813-5819.1991.

本文引用的文献

1
Control of experimental contact sensitivity.实验性接触敏感性的控制
Adv Immunol. 1980;30:121-57. doi: 10.1016/s0065-2776(08)60195-9.
2
T cell-mediated immunosuppression as an obstacle to adoptive immunotherapy of the P815 mastocytoma and its metastases.T细胞介导的免疫抑制是P815肥大细胞瘤及其转移灶过继性免疫治疗的障碍。
J Exp Med. 1981 Oct 1;154(4):1033-42. doi: 10.1084/jem.154.4.1033.
3
T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor.T细胞介导的抗肿瘤免疫抑制。免疫原性肿瘤进行性生长的一种解释。
J Exp Med. 1980 Jan 1;151(1):69-80. doi: 10.1084/jem.151.1.69.
4
Adoptive immunization against an established tumor with cytolytic versus memory T cells. Immediate versus delayed onset of regression.采用细胞溶解型T细胞与记忆性T细胞对已形成的肿瘤进行过继免疫。肿瘤消退的即时与延迟起始。
Transplantation. 1984 Jun;37(6):600-5. doi: 10.1097/00007890-198406000-00015.
5
Inhibition of the T suppressor circuit of delayed-type hypersensitivity by interferon.干扰素对迟发型超敏反应中T抑制性回路的抑制作用。
J Immunol. 1984 Nov;133(5):2412-6.
6
Suppressor T lymphocytes control the development of primary skin cancers in ultraviolet-irradiated mice.抑制性T淋巴细胞控制紫外线照射小鼠原发性皮肤癌的发展。
Science. 1982 Jun 4;216(4550):1133-4. doi: 10.1126/science.6210958.
7
Inhibition of suppressor T lymphocytes (Ts) by cimetidine.
J Immunol. 1987 May 1;138(9):2760-3.
8
Regulation of lymphocyte mitogenesis by (2'--5') oligo-isoadenylate.（2'-5'）寡聚异腺苷酸对淋巴细胞有丝分裂的调节作用
Nature. 1979;282(5741):849-51. doi: 10.1038/282849a0.
9
Hapten-specific T-cell responses to 4-hydroxy-3-nitrophenyl acetyl. II. Demonstration of idiotypic determinants on suppressor T cells.对半抗原4-羟基-3-硝基苯乙酰的特异性T细胞应答。II. 抑制性T细胞上独特型决定簇的证明。
J Exp Med. 1979 Oct 1;150(4):761-76. doi: 10.1084/jem.150.4.761.
10
Immune suppression with supraoptimal doses of antigen in contact sensitivity. I. Demonstration of suppressor cells and their sensitivity to cyclophosphamide.超最佳剂量抗原在接触性敏感反应中的免疫抑制作用。I. 抑制细胞的证实及其对环磷酰胺的敏感性
J Immunol. 1977 Jul;119(1):240-4.

小鼠β干扰素对抑制性T淋巴细胞的抑制作用

Inhibition of suppressor T lymphocytes by murine interferon beta.

作者信息

Sahasrabudhe D M

机构信息

Cancer Center, University of Rochester School of Medicine and Dentistry, New York 14642.

出版信息

J Exp Med. 1987 Nov 1;166(5):1573-8. doi: 10.1084/jem.166.5.1573.

DOI:10.1084/jem.166.5.1573
PMID:2960771
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2189656/
Abstract

We have presented data showing that IFN-beta at 1,000 U/mouse i.v. inhibits the generation of Ts-mediated tolerance to dinitrofluorobenzene (DNFB) and abrogates the transfer of suppression by Ts. We have also presented data showing that IFN-beta up to 10,000 U/mouse i.v. has no adverse effect on sensitization and elicitation. IFN-beta appears to be a suitable agent for evaluation as an adjunct in the immunotherapy of Ts inducing tumors.

摘要

我们已经展示的数据表明，静脉注射1000 U/只小鼠的干扰素β可抑制Ts介导的对二硝基氟苯（DNFB）耐受性的产生，并消除Ts介导的抑制作用的传递。我们还展示的数据表明，静脉注射高达10000 U/只小鼠的干扰素β对致敏和激发均无不良影响。干扰素β似乎是一种适合作为诱导Ts的肿瘤免疫治疗辅助药物进行评估的药物。