Zimber C, Ben-Efraim S, Weiss D W
Immunology. 1982 Mar;45(3):449-57.
Suppressor T cells acting on the efferent phase (Ts-eff) of dinitrofluorobenzene-contact sensitivity (DNFB-CS) were induced in BALB/c mice by injection of dinitrobenzenesulphonate (DNBSO3) and subsequent painting (sensitization) with DNFB. Ts-eff cells released a suppressor factor, antigen and strain specific, which was active in vivo in sensitized recipients. Administration of DNBSO3 alone generated suppressor T cells, which acted only on the afferent phase (Ts-aff). Suppressor T cells could not be detected in mice painted with DNFB and desensitized later by injection of DNBSO3.
通过注射二硝基苯磺酸盐(DNBSO3)并随后用二硝基氟苯(DNFB)涂抹(致敏),在BALB/c小鼠中诱导出作用于二硝基氟苯接触敏感性(DNFB-CS)传出相的抑制性T细胞(Ts-eff)。Ts-eff细胞释放出一种抑制因子,具有抗原性且具有菌株特异性,在致敏受体体内具有活性。单独给予DNBSO3可产生仅作用于传入相的抑制性T细胞(Ts-aff)。在用DNFB涂抹并随后通过注射DNBSO3进行脱敏的小鼠中未检测到抑制性T细胞。