Department of Environmental Health Engineering, Iranshahr University of Medical Sciences, Iranshahr, Iran.
Department of Environmental Health Engineering, Gonabad University of Medical Sciences, Gonabad, Iran.
Food Chem Toxicol. 2018 May;115:405-412. doi: 10.1016/j.fct.2018.03.040. Epub 2018 Mar 30.
An investigation of some heavy metals content in rice (Oryza sativa) and associated health risks was carried out for residents of Iranshahr city, Iran. Average daily rice consumption of the citizens and most widely used rice brands in the market of Iranshahr were determined using a questionnaire. Besides, the concentration of heavy metals in the gathered rice samples was measured by inductively coupled plasma mass spectrometry (ICP-MS). Monte Carlo uncertainty simulation was utilized in conducting exposure assessment and investigating the non-carcinogenic effects of the studied elements as well as the carcinogenic effect of As. Concentrations of As, Cd, Pb, Cu, Al, and Mo were 0.369 ± 0.094, 0.0337 ± 0.039, 0.123 ± 0.14, 3.095 ± 439.42, 39.6 ± 14.73, and 1.106 ± 0.133 mg kg, respectively. Al (0.18 ± 0.15 mg kg d) and Cd (0.00015 ± 0.00034 mg kg d) were the highest and lowest estimated daily intake, respectively. Except As (5.23 ± 4.01), the calculated hazard quotient for investigated elements showed no non-carcinogenic health risk. Besides, the simulation of the carcinogenic risk effect for As (2.37E-3) revealed that the ingestion of the studied rice brands would cause cancer risk due to lifetime consumption. Results show that consumption of rice in the Iranshahr city is a potential source of exposure to the studied elements.
伊朗伊兰沙赫尔市居民进行了一项关于大米(Oryza sativa)中某些重金属含量及其相关健康风险的调查。采用问卷调查的方式确定了市民的平均日大米消费量和市场上最常用的大米品牌。此外,还采用电感耦合等离子体质谱法(ICP-MS)测量了采集的大米样本中重金属的浓度。通过蒙特卡罗不确定性模拟,对研究元素的非致癌影响以及 As 的致癌作用进行了暴露评估。As、Cd、Pb、Cu、Al 和 Mo 的浓度分别为 0.369±0.094、0.0337±0.039、0.123±0.14、3.095±439.42、39.6±14.73 和 1.106±0.133mgkg。Al(0.18±0.15mgkg d)和 Cd(0.00015±0.00034mgkg d)的估计日摄入量最高和最低。除 As(5.23±4.01)外,所研究元素的计算危害商没有显示出非致癌健康风险。此外,As(2.37E-3)致癌风险效应的模拟表明,由于终生消费,食用研究中所涉及的大米品牌会导致癌症风险。结果表明,在伊兰沙赫尔市食用大米可能是暴露于所研究元素的潜在来源。