Department of Environmental Health, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Student Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Environ Sci Pollut Res Int. 2018 Nov;25(31):30928-30937. doi: 10.1007/s11356-018-3030-y. Epub 2018 Sep 4.
In the current study, the concentration of heavy metals including lead (Pb), chromium (Cr), cadmium (Cd), and aluminum (Al) in commonly instant noodles consumed in Iran (either imported from other countries or produced in Iran) was investigated by acid digestion method followed by an inductively coupled plasma optical emission spectrometry system (ICP-OES). Also, the associated non-carcinogenic risk due to ingestion of heavy metals for adults and children was estimated by calculating percentile 95% target hazard quotient (THQ) in the Monte Carlo simulation (MCS) method. The average concentrations of Pb, Cr, Cd, and Al in Iranian instant noodle samples were measured as 1.21 ± 0.81, 0.08 ± 0.10, 0.03 ± 0.06, and 9.15 ± 4.82 (mg/kg) and in imported instant noodle samples were 1.00 ± 0.61, 0.07 ± 0.07, 0.04 ± 0.03, and 15.90 ± 0.93 (mg/kg), respectively. A significant difference (p value < 0.05) in the mean concentration of Pb, Cr, Cd, and Al of Iranian instant noodle and imported instant noodle samples was observed. Also, the concentration of Pb, Cr, Cd, and Al in all brands of instant noodle (0.025 mg/kg, 0.050 mg/kg, 0.003 mg/kg, and 0.237 mg/kg, respectively) surpassed the WHO-permitted limits for Pb, Cr, Cd, and Al. Percentile 95% of THQ of Pb, Cr, Cd, and Al for the adult consumers was calculated as 0.012, 0.000007, 0.010, and 1.789; while in the case of children, percentile 95% of THQ of Pb, Cr, Cd, and Al was defined as 0.044, 0.00023, 0.035, and 6.167, respectively. Health risk assessment indicated that both adults and children are at considerable non-carcinogenic health risk for Al (THQ > 1). Therefore, approaching the required strategies in order to reduce the concentration of heavy metals particularly Al in the instant noodle is recommended.
在目前的研究中,通过酸消解法和电感耦合等离子体发射光谱系统(ICP-OES)对伊朗(无论是从其他国家进口还是在伊朗生产)消费的普通方便面中包括铅(Pb)、铬(Cr)、镉(Cd)和铝(Al)在内的重金属浓度进行了调查。此外,还通过蒙特卡罗模拟(MCS)法计算百分位 95%目标危害系数(THQ),估算了成人和儿童因摄入重金属而产生的非致癌风险。伊朗方便面样品中 Pb、Cr、Cd 和 Al 的平均浓度分别为 1.21±0.81、0.08±0.10、0.03±0.06 和 9.15±4.82(mg/kg),进口方便面样品中 Pb、Cr、Cd 和 Al 的浓度分别为 1.00±0.61、0.07±0.07、0.04±0.03 和 15.90±0.93(mg/kg)。伊朗方便面和进口方便面样品中 Pb、Cr、Cd 和 Al 的平均浓度存在显著差异(p 值<0.05)。此外,所有品牌方便面中 Pb、Cr、Cd 和 Al 的浓度(分别为 0.025 mg/kg、0.050 mg/kg、0.003 mg/kg 和 0.237 mg/kg)均超过了世界卫生组织允许的 Pb、Cr、Cd 和 Al 限量。成人消费者的 Pb、Cr、Cd 和 Al 的百分位 95%THQ 分别计算为 0.012、0.000007、0.010 和 1.789;而对于儿童,Pb、Cr、Cd 和 Al 的百分位 95%THQ 分别定义为 0.044、0.00023、0.035 和 6.167。健康风险评估表明,成人和儿童都面临着相当大的非致癌健康风险,尤其是 Al(THQ>1)。因此,建议采取必要的策略,以降低方便面中重金属特别是 Al 的浓度。