Zwas S T, Walden R, Elkanovitz R, Bochurowski S, Bass A
Department of Nuclear Medicine, Chaim Sheba Medical Centre, Tel-Hashomer, Israel.
Nucl Med Commun. 1987 Sep;8(9):727-32. doi: 10.1097/00006231-198709000-00004.
Arterial grafts were studied with indium-III-labelled platelets in 13 patients (18 graft limbs) in the early post-implication period. Platelet thrombogenic activity was graded into four grades by visual inspection of the images, and scintigraphic criteria of impending graft occlusion were defined. Dacron and polytetrafluoroethylene grafts had similar high thrombogenic activity in comparison with autologous veins. Nine graft studies showed patterns of radioactivity concentration that suggested threatening thrombosis and eight of these eventually occluded. In nine other studies absent to moderate radiolabelled platelet activity was observed and none occluded within a mean follow-up period of 24 months. Prediction of graft occlusion of scintigraphic evaluation using the present simple non-invasive technique is valuable since corrective measures may be instituted earlier and with greater success in the post-operative follow-up period.
在术后早期，对13例患者（18条移植肢体）的动脉移植物进行了铟-III标记血小板的研究。通过目视检查图像将血小板血栓形成活性分为四个等级，并确定了移植物即将闭塞的闪烁显像标准。与自体静脉相比，涤纶和聚四氟乙烯移植物具有相似的高血栓形成活性。九项移植物研究显示放射性浓度模式提示有威胁性血栓形成，其中八项最终闭塞。在其他九项研究中，观察到放射性标记血小板活性缺失至中等，在平均24个月的随访期内无一例闭塞。使用目前这种简单的非侵入性技术进行闪烁显像评估来预测移植物闭塞是有价值的，因为在术后随访期可以更早地采取纠正措施并取得更大成功。
