IEEE Trans Ultrason Ferroelectr Freq Control. 2018 Apr;65(4):589-599. doi: 10.1109/TUFFC.2018.2794220.
Video capsule endoscopy (VCE) has significantly advanced visualization of the gastrointestinal tract since its introduction in the last 20 years. Work is now under way to combine VCE with microultrasound imaging. However, small maximum capsule dimensions, coupled with the electronics required to integrate ultrasound imaging capabilities, pose significant design challenges. This paper describes a simulation process for testing transducer geometries and imaging methodologies to achieve satisfactory imaging performance within the physical limitations of the capsule size and outlines many of the tradeoffs needed in the design of this new class of ultrasound capsule endoscopy (USCE) device. A hybrid MATLAB model is described, incorporating Krimholtz-Leedom-Matthaei circuit elements and digitizing and beamforming elements to render a gray-scale B-mode. This model is combined with a model of acoustic propagation to generate images of point scatterers. The models are used to demonstrate the performance of a USCE transducer configuration comprising a single, unfocused transmit ring of radius 5 mm separated into eight segments for electrical impedance control and a 512-element receive linear array, also formed into a ring. The MATLAB model includes an ultrasonic pulser circuit connected to a piezocrystal composite transmit transducer with a center frequency of 25 MHz. B-scan images are simulated for wire target phantoms, multilayered phantoms, and a gut wall model. To demonstrate the USCE system's ability to image tissue, a digital phantom was created from single-element ultrasonic transducer scans of porcine small bowel ex vivo obtained at a frequency of 45 MHz.
视频胶囊内镜(VCE)自 20 年前问世以来,大大提高了胃肠道的可视化程度。目前正在努力将 VCE 与微超声成像相结合。然而,胶囊的最大尺寸较小,加上集成超声成像功能所需的电子设备,这给设计带来了巨大的挑战。本文介绍了一种用于测试换能器几何形状和成像方法的仿真过程,以在胶囊尺寸的物理限制内实现令人满意的成像性能,并概述了在这种新型超声胶囊内镜(USCE)设备设计中需要进行的许多权衡。描述了一个混合的 MATLAB 模型,该模型包含了 Krimholtz-Leedom-Matthaei 电路元件以及数字化和波束形成元件,以呈现灰度 B 模式。该模型与声传播模型相结合,生成点散射体的图像。该模型用于演示由单个、无焦点的半径为 5mm 的发射环组成的 USCE 换能器配置的性能,该发射环被分成八个部分用于电组抗控制,以及一个 512 个元素的接收线性阵列,也形成一个环。MATLAB 模型包括一个与中心频率为 25MHz 的压电器件复合发射换能器相连的超声脉冲器电路。针对线靶体、多层体模和肠壁模型模拟了 B 扫描图像。为了展示 USCE 系统对组织成像的能力,创建了一个数字体模,该体模是通过对离体猪小肠进行的 45MHz 频率的单个超声换能器扫描获得的。