Basse Idrissa, Diagne/Gueye Ndéye Rama, Ndiaye Ndiémé, Mbengue Marie, Obambi Dina Cyrienne, Ba Aïssatou, Fall Amadou Lamine, Ndongo Aliou Abdoulaye, Boiro Djibril, Ba Abou
Service de Pédiatrie, Hôpital pour Enfants de Diamniadio, Université de Thiès, Sénégal.
Service de Radiologie, Hôpital pour Enfants de Diamniadio, Sénégal.
Pan Afr Med J. 2017 Nov 7;28:206. doi: 10.11604/pamj.2017.28.206.11639. eCollection 2017.
CVT is generally rare, particularly among infants. The occurrence of a SAH associated with CVT is very uncommon and only a few cases have been reported in the literature. Symptoms are variable and often misleading. Outcome can be lethal or it can cause potentially severe sequelae if it is not treated or treated late. We report the case of a 22-month old infant examined for convulsions with Stage II coma, intracranial hypertension syndrome and infectious syndrome. Laboratory tests showed pseudomonas spp sepsis and cerebral CT scan allowed the diagnosis. Treatment was based on antibiotic therapy but mainly on anticoagulation therapy. The patient had a significant clinical improvement and follow-up cerebral CT scan showed disappearance of thrombosis with sequellar right hemoragic images. CVT is a severe disease, usually of infectious origin. Anticoagulant therapy is controversial, in particular in patients with associated hemorrhage, but clinical experience supports the effectiveness and safety of this treatment.
脑静脉窦血栓形成(CVT)通常较为罕见,在婴儿中尤其如此。与CVT相关的蛛网膜下腔出血(SAH)的发生非常少见,文献中仅报道过少数病例。症状多变,常常具有误导性。如果不治疗或治疗延迟,后果可能是致命的,或者会导致潜在的严重后遗症。我们报告了一例22个月大的婴儿,因惊厥接受检查,伴有II期昏迷、颅内高压综合征和感染综合征。实验室检查显示为假单胞菌属败血症,脑部CT扫描得以确诊。治疗基于抗生素治疗,但主要是抗凝治疗。患者临床有显著改善,后续脑部CT扫描显示血栓消失,伴有右侧出血性后遗症影像。CVT是一种严重疾病,通常由感染引起。抗凝治疗存在争议,尤其是在伴有出血的患者中,但临床经验支持这种治疗的有效性和安全性。