Rascher W, Seyberth H W
Department of Pediatrics, Children's Hospital of the University of Heidelberg, West Germany.
Arch Dis Child. 1987 Nov;62(11):1165-7. doi: 10.1136/adc.62.11.1165.
Preterm infants with symptomatic patent ductus arteriosus had considerably raised plasma concentrations of atrial natriuretic peptide. Surgical ligation of the patent ductus arteriosus was associated with an immediate fall in plasma atrial natriuretic peptide concentration. Thus left to right shunting and left atrial distension may cause atrial natriuretic peptide release in preterm infants with patent ductus arteriosus.
有症状的动脉导管未闭早产儿的血浆心房利钠肽浓度显著升高。动脉导管未闭的手术结扎与血浆心房利钠肽浓度立即下降有关。因此，左向右分流和左心房扩张可能导致动脉导管未闭早产儿释放心房利钠肽。
